UV laser footprinting and DNA-protein crosslinking

Dimitar Angelov, Stefan Dimitrov, Jean Cadet

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The application of ultraviolet lasers for studying interactions such as footprinting and protein-DNA crosslinking formations was discussed. The crosslinking reaction was completed in less than a microsecond that allowed the existing protein-DNA interactions to freeze. Irradiation of protein-DNA complexes with single ultraviolet laser pulses results in the formation of a spectrum of photodamage in DNA, the indution and the efficiency of the different lesions that are dependent on the presence of the specific proteins in the complexes.

Original languageEnglish
Title of host publicationIQEC, International Quantum Electronics Conference Proceedings
PublisherIEEE
Pages234
Number of pages1
Publication statusPublished - 2000
Externally publishedYes
Event2000 International Quantum Electronics Conference (IQEC 2000) - Nice, France
Duration: 10 Sep 200015 Sep 2000

Other

Other2000 International Quantum Electronics Conference (IQEC 2000)
CityNice, France
Period10/9/0015/9/00

Fingerprint

crosslinking
ultraviolet lasers
deoxyribonucleic acid
proteins
lesions
interactions
irradiation
pulses

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Angelov, D., Dimitrov, S., & Cadet, J. (2000). UV laser footprinting and DNA-protein crosslinking. In IQEC, International Quantum Electronics Conference Proceedings (pp. 234). IEEE.

UV laser footprinting and DNA-protein crosslinking. / Angelov, Dimitar; Dimitrov, Stefan; Cadet, Jean.

IQEC, International Quantum Electronics Conference Proceedings. IEEE, 2000. p. 234.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Angelov, D, Dimitrov, S & Cadet, J 2000, UV laser footprinting and DNA-protein crosslinking. in IQEC, International Quantum Electronics Conference Proceedings. IEEE, pp. 234, 2000 International Quantum Electronics Conference (IQEC 2000), Nice, France, 10/9/00.
Angelov D, Dimitrov S, Cadet J. UV laser footprinting and DNA-protein crosslinking. In IQEC, International Quantum Electronics Conference Proceedings. IEEE. 2000. p. 234
Angelov, Dimitar ; Dimitrov, Stefan ; Cadet, Jean. / UV laser footprinting and DNA-protein crosslinking. IQEC, International Quantum Electronics Conference Proceedings. IEEE, 2000. pp. 234
@inproceedings{57f11250142a4872894c5bc741fc4ae5,
title = "UV laser footprinting and DNA-protein crosslinking",
abstract = "The application of ultraviolet lasers for studying interactions such as footprinting and protein-DNA crosslinking formations was discussed. The crosslinking reaction was completed in less than a microsecond that allowed the existing protein-DNA interactions to freeze. Irradiation of protein-DNA complexes with single ultraviolet laser pulses results in the formation of a spectrum of photodamage in DNA, the indution and the efficiency of the different lesions that are dependent on the presence of the specific proteins in the complexes.",
author = "Dimitar Angelov and Stefan Dimitrov and Jean Cadet",
year = "2000",
language = "English",
pages = "234",
booktitle = "IQEC, International Quantum Electronics Conference Proceedings",
publisher = "IEEE",

}

TY - GEN

T1 - UV laser footprinting and DNA-protein crosslinking

AU - Angelov, Dimitar

AU - Dimitrov, Stefan

AU - Cadet, Jean

PY - 2000

Y1 - 2000

N2 - The application of ultraviolet lasers for studying interactions such as footprinting and protein-DNA crosslinking formations was discussed. The crosslinking reaction was completed in less than a microsecond that allowed the existing protein-DNA interactions to freeze. Irradiation of protein-DNA complexes with single ultraviolet laser pulses results in the formation of a spectrum of photodamage in DNA, the indution and the efficiency of the different lesions that are dependent on the presence of the specific proteins in the complexes.

AB - The application of ultraviolet lasers for studying interactions such as footprinting and protein-DNA crosslinking formations was discussed. The crosslinking reaction was completed in less than a microsecond that allowed the existing protein-DNA interactions to freeze. Irradiation of protein-DNA complexes with single ultraviolet laser pulses results in the formation of a spectrum of photodamage in DNA, the indution and the efficiency of the different lesions that are dependent on the presence of the specific proteins in the complexes.

UR - http://www.scopus.com/inward/record.url?scp=0033696882&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033696882&partnerID=8YFLogxK

M3 - Conference contribution

SP - 234

BT - IQEC, International Quantum Electronics Conference Proceedings

PB - IEEE

ER -