Use of stem cells as carriers of oncolytic viruses for cancer treatment

Elham Zendedel, Stephen Atkin, Amirhossein Sahebkar

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Therapeutic application of stem cells and oncolytic viruses in cancer treatment has rapidly increased in the last decade. Oncolytic viruses are considered as a new class of anticancer agents because of their ability to selectively infect and destroy cancer cells. Furthermore, regarding the specific migratory capacity of stem cells, they can be used as carriers or vectors targeting metastatic cancer. Promising results have been reported regarding the use of stem cells and oncolytic viruses as a therapeutic approach for the treatment of metastatic cancer. The present review aimed to determine the approaches involved in the use of the tumor-homing capacity of stem cells for cancer treatment.

Original languageEnglish
JournalJournal of Cellular Physiology
DOIs
Publication statusPublished - 1 Jan 2019

Fingerprint

Oncolytic Viruses
Oncology
Stem cells
Viruses
Stem Cells
Neoplasms
Antineoplastic Agents
Neoplastic Stem Cells
Tumors
Cells
Therapeutics

Keywords

  • cancer treatment
  • metastatic cancer
  • oncolytic virotherapy
  • stem cell

ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Cell Biology

Cite this

Use of stem cells as carriers of oncolytic viruses for cancer treatment. / Zendedel, Elham; Atkin, Stephen; Sahebkar, Amirhossein.

In: Journal of Cellular Physiology, 01.01.2019.

Research output: Contribution to journalReview article

@article{896c91e803c54649bb6ec7ba2bdc5660,
title = "Use of stem cells as carriers of oncolytic viruses for cancer treatment",
abstract = "Therapeutic application of stem cells and oncolytic viruses in cancer treatment has rapidly increased in the last decade. Oncolytic viruses are considered as a new class of anticancer agents because of their ability to selectively infect and destroy cancer cells. Furthermore, regarding the specific migratory capacity of stem cells, they can be used as carriers or vectors targeting metastatic cancer. Promising results have been reported regarding the use of stem cells and oncolytic viruses as a therapeutic approach for the treatment of metastatic cancer. The present review aimed to determine the approaches involved in the use of the tumor-homing capacity of stem cells for cancer treatment.",
keywords = "cancer treatment, metastatic cancer, oncolytic virotherapy, stem cell",
author = "Elham Zendedel and Stephen Atkin and Amirhossein Sahebkar",
year = "2019",
month = "1",
day = "1",
doi = "10.1002/jcp.28320",
language = "English",
journal = "Journal of Cellular Physiology",
issn = "0021-9541",
publisher = "Wiley-Liss Inc.",

}

TY - JOUR

T1 - Use of stem cells as carriers of oncolytic viruses for cancer treatment

AU - Zendedel, Elham

AU - Atkin, Stephen

AU - Sahebkar, Amirhossein

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Therapeutic application of stem cells and oncolytic viruses in cancer treatment has rapidly increased in the last decade. Oncolytic viruses are considered as a new class of anticancer agents because of their ability to selectively infect and destroy cancer cells. Furthermore, regarding the specific migratory capacity of stem cells, they can be used as carriers or vectors targeting metastatic cancer. Promising results have been reported regarding the use of stem cells and oncolytic viruses as a therapeutic approach for the treatment of metastatic cancer. The present review aimed to determine the approaches involved in the use of the tumor-homing capacity of stem cells for cancer treatment.

AB - Therapeutic application of stem cells and oncolytic viruses in cancer treatment has rapidly increased in the last decade. Oncolytic viruses are considered as a new class of anticancer agents because of their ability to selectively infect and destroy cancer cells. Furthermore, regarding the specific migratory capacity of stem cells, they can be used as carriers or vectors targeting metastatic cancer. Promising results have been reported regarding the use of stem cells and oncolytic viruses as a therapeutic approach for the treatment of metastatic cancer. The present review aimed to determine the approaches involved in the use of the tumor-homing capacity of stem cells for cancer treatment.

KW - cancer treatment

KW - metastatic cancer

KW - oncolytic virotherapy

KW - stem cell

UR - http://www.scopus.com/inward/record.url?scp=85061573939&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85061573939&partnerID=8YFLogxK

U2 - 10.1002/jcp.28320

DO - 10.1002/jcp.28320

M3 - Review article

JO - Journal of Cellular Physiology

JF - Journal of Cellular Physiology

SN - 0021-9541

ER -