Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls

Ronette L. Kolotkin, Ross D. Crosby, Richard E. Gress, Steven Hunt, Ted D. Adams

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

Background: Few weight loss surgery trials have evaluated the changes in health-related quality of life (HRQOL) relative to obese individuals not participating in weight loss interventions. In a prospective study at a bariatric surgery practice, we evaluated the 2-year changes in HRQOL in gastric bypass patients compared with 2 severely obese groups who did not undergo surgical weight loss. Methods: A total of 308 gastric bypass patients were compared with 253 individuals who sought but did not undergo gastric bypass and 272 population-based obese individuals using the weight-related (Impact of Weight on Quality of Life-Lite) and general (Medical Outcomes Study 36-item Short-Form Health Survey) HRQOL questionnaires at baseline and 2 years of follow-up. Results: The percentage of weight loss was 34.2% for the gastric bypass and 1.4% for the no gastric bypass groups, with a .5% gain for population-based obese group. Both measures of HRQOL showed greater improvements for the gastric bypass group, even after controlling for baseline differences. Effect sizes for changes in physical and weight-related HRQOL were very large for gastric bypass, but small to medium for the 2 comparison groups. Effect sizes for changes in the psychosocial aspects of HRQOL were moderate to very large for gastric bypass, but small for the 2 comparison groups. Of the gastric bypass patients, 97% had meaningful improvements in the Impact of Weight on Quality of Life-Lite total score compared with 43% of the no gastric bypass group and 30% of the population-based obese group. Conclusion: Dramatic improvements had occurred in weight-related and physical HRQOL for gastric bypass patients at 2 years after surgery compared with 2 severely obese groups who had not undergone surgery. These results support the effectiveness of gastric bypass surgery in improving patients' HRQOL.

Original languageEnglish
Pages (from-to)250-256
Number of pages7
JournalSurgery for Obesity and Related Diseases
Volume5
Issue number2
DOIs
Publication statusPublished - Mar 2009
Externally publishedYes

Fingerprint

Gastric Bypass
Quality of Life
Weight Loss
Weights and Measures
Bariatric Surgery
Health Surveys
Population Groups
Population
Outcome Assessment (Health Care)
Prospective Studies

Keywords

  • Cohort trial
  • Gastric bypass surgery
  • Health-related quality of life
  • HRQOL
  • Impact of Weight on Quality of Life-Lite
  • IWQOL-Lite
  • Medical Outcomes Study 36-item Short-Form Health Survey
  • SF-36

ASJC Scopus subject areas

  • Surgery

Cite this

Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls. / Kolotkin, Ronette L.; Crosby, Ross D.; Gress, Richard E.; Hunt, Steven; Adams, Ted D.

In: Surgery for Obesity and Related Diseases, Vol. 5, No. 2, 03.2009, p. 250-256.

Research output: Contribution to journalArticle

Kolotkin, Ronette L. ; Crosby, Ross D. ; Gress, Richard E. ; Hunt, Steven ; Adams, Ted D. / Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls. In: Surgery for Obesity and Related Diseases. 2009 ; Vol. 5, No. 2. pp. 250-256.
@article{1ec788be08c24304a27cff2aa74520ed,
title = "Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls",
abstract = "Background: Few weight loss surgery trials have evaluated the changes in health-related quality of life (HRQOL) relative to obese individuals not participating in weight loss interventions. In a prospective study at a bariatric surgery practice, we evaluated the 2-year changes in HRQOL in gastric bypass patients compared with 2 severely obese groups who did not undergo surgical weight loss. Methods: A total of 308 gastric bypass patients were compared with 253 individuals who sought but did not undergo gastric bypass and 272 population-based obese individuals using the weight-related (Impact of Weight on Quality of Life-Lite) and general (Medical Outcomes Study 36-item Short-Form Health Survey) HRQOL questionnaires at baseline and 2 years of follow-up. Results: The percentage of weight loss was 34.2{\%} for the gastric bypass and 1.4{\%} for the no gastric bypass groups, with a .5{\%} gain for population-based obese group. Both measures of HRQOL showed greater improvements for the gastric bypass group, even after controlling for baseline differences. Effect sizes for changes in physical and weight-related HRQOL were very large for gastric bypass, but small to medium for the 2 comparison groups. Effect sizes for changes in the psychosocial aspects of HRQOL were moderate to very large for gastric bypass, but small for the 2 comparison groups. Of the gastric bypass patients, 97{\%} had meaningful improvements in the Impact of Weight on Quality of Life-Lite total score compared with 43{\%} of the no gastric bypass group and 30{\%} of the population-based obese group. Conclusion: Dramatic improvements had occurred in weight-related and physical HRQOL for gastric bypass patients at 2 years after surgery compared with 2 severely obese groups who had not undergone surgery. These results support the effectiveness of gastric bypass surgery in improving patients' HRQOL.",
keywords = "Cohort trial, Gastric bypass surgery, Health-related quality of life, HRQOL, Impact of Weight on Quality of Life-Lite, IWQOL-Lite, Medical Outcomes Study 36-item Short-Form Health Survey, SF-36",
author = "Kolotkin, {Ronette L.} and Crosby, {Ross D.} and Gress, {Richard E.} and Steven Hunt and Adams, {Ted D.}",
year = "2009",
month = "3",
doi = "10.1016/j.soard.2009.01.009",
language = "English",
volume = "5",
pages = "250--256",
journal = "Surgery for Obesity and Related Diseases",
issn = "1550-7289",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls

AU - Kolotkin, Ronette L.

AU - Crosby, Ross D.

AU - Gress, Richard E.

AU - Hunt, Steven

AU - Adams, Ted D.

PY - 2009/3

Y1 - 2009/3

N2 - Background: Few weight loss surgery trials have evaluated the changes in health-related quality of life (HRQOL) relative to obese individuals not participating in weight loss interventions. In a prospective study at a bariatric surgery practice, we evaluated the 2-year changes in HRQOL in gastric bypass patients compared with 2 severely obese groups who did not undergo surgical weight loss. Methods: A total of 308 gastric bypass patients were compared with 253 individuals who sought but did not undergo gastric bypass and 272 population-based obese individuals using the weight-related (Impact of Weight on Quality of Life-Lite) and general (Medical Outcomes Study 36-item Short-Form Health Survey) HRQOL questionnaires at baseline and 2 years of follow-up. Results: The percentage of weight loss was 34.2% for the gastric bypass and 1.4% for the no gastric bypass groups, with a .5% gain for population-based obese group. Both measures of HRQOL showed greater improvements for the gastric bypass group, even after controlling for baseline differences. Effect sizes for changes in physical and weight-related HRQOL were very large for gastric bypass, but small to medium for the 2 comparison groups. Effect sizes for changes in the psychosocial aspects of HRQOL were moderate to very large for gastric bypass, but small for the 2 comparison groups. Of the gastric bypass patients, 97% had meaningful improvements in the Impact of Weight on Quality of Life-Lite total score compared with 43% of the no gastric bypass group and 30% of the population-based obese group. Conclusion: Dramatic improvements had occurred in weight-related and physical HRQOL for gastric bypass patients at 2 years after surgery compared with 2 severely obese groups who had not undergone surgery. These results support the effectiveness of gastric bypass surgery in improving patients' HRQOL.

AB - Background: Few weight loss surgery trials have evaluated the changes in health-related quality of life (HRQOL) relative to obese individuals not participating in weight loss interventions. In a prospective study at a bariatric surgery practice, we evaluated the 2-year changes in HRQOL in gastric bypass patients compared with 2 severely obese groups who did not undergo surgical weight loss. Methods: A total of 308 gastric bypass patients were compared with 253 individuals who sought but did not undergo gastric bypass and 272 population-based obese individuals using the weight-related (Impact of Weight on Quality of Life-Lite) and general (Medical Outcomes Study 36-item Short-Form Health Survey) HRQOL questionnaires at baseline and 2 years of follow-up. Results: The percentage of weight loss was 34.2% for the gastric bypass and 1.4% for the no gastric bypass groups, with a .5% gain for population-based obese group. Both measures of HRQOL showed greater improvements for the gastric bypass group, even after controlling for baseline differences. Effect sizes for changes in physical and weight-related HRQOL were very large for gastric bypass, but small to medium for the 2 comparison groups. Effect sizes for changes in the psychosocial aspects of HRQOL were moderate to very large for gastric bypass, but small for the 2 comparison groups. Of the gastric bypass patients, 97% had meaningful improvements in the Impact of Weight on Quality of Life-Lite total score compared with 43% of the no gastric bypass group and 30% of the population-based obese group. Conclusion: Dramatic improvements had occurred in weight-related and physical HRQOL for gastric bypass patients at 2 years after surgery compared with 2 severely obese groups who had not undergone surgery. These results support the effectiveness of gastric bypass surgery in improving patients' HRQOL.

KW - Cohort trial

KW - Gastric bypass surgery

KW - Health-related quality of life

KW - HRQOL

KW - Impact of Weight on Quality of Life-Lite

KW - IWQOL-Lite

KW - Medical Outcomes Study 36-item Short-Form Health Survey

KW - SF-36

UR - http://www.scopus.com/inward/record.url?scp=62549094873&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=62549094873&partnerID=8YFLogxK

U2 - 10.1016/j.soard.2009.01.009

DO - 10.1016/j.soard.2009.01.009

M3 - Article

C2 - 19306822

AN - SCOPUS:62549094873

VL - 5

SP - 250

EP - 256

JO - Surgery for Obesity and Related Diseases

JF - Surgery for Obesity and Related Diseases

SN - 1550-7289

IS - 2

ER -