Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls

Ronette L. Kolotkin, Ross D. Crosby, Richard E. Gress, Steven Hunt, Ted D. Adams

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90 Citations (Scopus)

Abstract

Background: Few weight loss surgery trials have evaluated the changes in health-related quality of life (HRQOL) relative to obese individuals not participating in weight loss interventions. In a prospective study at a bariatric surgery practice, we evaluated the 2-year changes in HRQOL in gastric bypass patients compared with 2 severely obese groups who did not undergo surgical weight loss. Methods: A total of 308 gastric bypass patients were compared with 253 individuals who sought but did not undergo gastric bypass and 272 population-based obese individuals using the weight-related (Impact of Weight on Quality of Life-Lite) and general (Medical Outcomes Study 36-item Short-Form Health Survey) HRQOL questionnaires at baseline and 2 years of follow-up. Results: The percentage of weight loss was 34.2% for the gastric bypass and 1.4% for the no gastric bypass groups, with a .5% gain for population-based obese group. Both measures of HRQOL showed greater improvements for the gastric bypass group, even after controlling for baseline differences. Effect sizes for changes in physical and weight-related HRQOL were very large for gastric bypass, but small to medium for the 2 comparison groups. Effect sizes for changes in the psychosocial aspects of HRQOL were moderate to very large for gastric bypass, but small for the 2 comparison groups. Of the gastric bypass patients, 97% had meaningful improvements in the Impact of Weight on Quality of Life-Lite total score compared with 43% of the no gastric bypass group and 30% of the population-based obese group. Conclusion: Dramatic improvements had occurred in weight-related and physical HRQOL for gastric bypass patients at 2 years after surgery compared with 2 severely obese groups who had not undergone surgery. These results support the effectiveness of gastric bypass surgery in improving patients' HRQOL.

Original languageEnglish
Pages (from-to)250-256
Number of pages7
JournalSurgery for Obesity and Related Diseases
Volume5
Issue number2
DOIs
Publication statusPublished - Mar 2009
Externally publishedYes

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Keywords

  • Cohort trial
  • Gastric bypass surgery
  • Health-related quality of life
  • HRQOL
  • Impact of Weight on Quality of Life-Lite
  • IWQOL-Lite
  • Medical Outcomes Study 36-item Short-Form Health Survey
  • SF-36

ASJC Scopus subject areas

  • Surgery

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