Since its discovery, ferrocene and its derivatives have been attracting much attention ranging from the viewpoint of catalysis, organic synthesis, new materials andsupramolecular chemistry. Accordingly, in recent years a considerable amount of research has been devoted to the synthesis of various substituted ferrocenes. The widespread use of transition metal catalysts for the introduction of novel functional groups opened a new way in synthetic chemistry in the last two decades. Enhanced selectivity, mild reaction conditions, well-defined mechanism, and the applicability of standard techniques make this methodology an attractive alternative to conventional organic or organometallic reactions in the synthesis of ferrocene derivatives, too. The abundance of recent results and challenging problems encouraged us to summarize the most important ideas and methodologies, on the application of ferrocene derivatives as substrates. In this chapter, the most important achievements of the last 10 years are surveyed. The results show that the number of homogeneous catalytic reaction types used in ferrocene synthesis is steadily increasing and these methods have a great potential in the synthesis of both achiral and chiral derivatives of ferrocene. Chiral ferrocenyl alcohols, as key intermediates towards various chiral ligands, have been synthesized by asymmetric hydrogenation and dihydroxylation methods. Hydrosilylation has effectively been used for the synthesis of simple silicon-containing ferrocene derivatives as well as for the construction of interesting molecular architectures.
|Title of host publication||Ferrocenes: Compounds, Properties and Applications|
|Publisher||Nova Science Publishers, Inc.|
|Number of pages||41|
|Publication status||Published - Jan 2011|
ASJC Scopus subject areas
- Chemical Engineering(all)