Transforming growth factor β signaling, vascular remodeling, and hypertension

Phyllis August, Manikkam Suthanthiran

Research output: Contribution to journalShort survey

52 Citations (Scopus)

Abstract

Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation, together with the finding that Emilin1 regulates the availability of transforming growth factor β (TGF-β), contributes to a growing body of evidence implicating TGF-β in hypertension.

Original languageEnglish
JournalNew England Journal of Medicine
Volume354
Issue number25
DOIs
Publication statusPublished - 22 Jun 2006
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

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