Transforming growth factor β signaling, vascular remodeling, and hypertension

Phyllis August, Manikkam Suthanthiran

Research output: Contribution to journalShort survey

52 Citations (Scopus)


Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation, together with the finding that Emilin1 regulates the availability of transforming growth factor β (TGF-β), contributes to a growing body of evidence implicating TGF-β in hypertension.

Original languageEnglish
JournalNew England Journal of Medicine
Issue number25
Publication statusPublished - 22 Jun 2006
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)

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