Transforming growth factor β signaling, vascular remodeling, and hypertension

Phyllis August, Manikkam Suthanthiran

Research output: Contribution to journalShort survey

50 Citations (Scopus)

Abstract

Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation, together with the finding that Emilin1 regulates the availability of transforming growth factor β (TGF-β), contributes to a growing body of evidence implicating TGF-β in hypertension.

Original languageEnglish
JournalNew England Journal of Medicine
Volume354
Issue number25
DOIs
Publication statusPublished - 22 Jun 2006
Externally publishedYes

Fingerprint

Transforming Growth Factors
Hypertension
Blood Vessels
Intercellular Signaling Peptides and Proteins
Vascular Remodeling

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Transforming growth factor β signaling, vascular remodeling, and hypertension. / August, Phyllis; Suthanthiran, Manikkam.

In: New England Journal of Medicine, Vol. 354, No. 25, 22.06.2006.

Research output: Contribution to journalShort survey

@article{3a17670880d14853ba312d623f490d2c,
title = "Transforming growth factor β signaling, vascular remodeling, and hypertension",
abstract = "Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation, together with the finding that Emilin1 regulates the availability of transforming growth factor β (TGF-β), contributes to a growing body of evidence implicating TGF-β in hypertension.",
author = "Phyllis August and Manikkam Suthanthiran",
year = "2006",
month = "6",
day = "22",
doi = "10.1056/NEJMcibr062143",
language = "English",
volume = "354",
journal = "New England Journal of Medicine",
issn = "0028-4793",
publisher = "Massachussetts Medical Society",
number = "25",

}

TY - JOUR

T1 - Transforming growth factor β signaling, vascular remodeling, and hypertension

AU - August, Phyllis

AU - Suthanthiran, Manikkam

PY - 2006/6/22

Y1 - 2006/6/22

N2 - Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation, together with the finding that Emilin1 regulates the availability of transforming growth factor β (TGF-β), contributes to a growing body of evidence implicating TGF-β in hypertension.

AB - Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation, together with the finding that Emilin1 regulates the availability of transforming growth factor β (TGF-β), contributes to a growing body of evidence implicating TGF-β in hypertension.

UR - http://www.scopus.com/inward/record.url?scp=33745243399&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745243399&partnerID=8YFLogxK

U2 - 10.1056/NEJMcibr062143

DO - 10.1056/NEJMcibr062143

M3 - Short survey

VL - 354

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 25

ER -