Tolerability and effectiveness of lamotrigine in complex elderly patients

Jasdeep S. Aulakh, James W. Hawkins, Herman S. Athwal, Javaid I. Sheikh, Jerome Yesavage, Jared R. Tinklenberg

Research output: Contribution to journalReview article

14 Citations (Scopus)


There is paucity of medical literature on the use of lamotrigine in elderly patients who have behavior problems and diverse psychiatric syndromes. This article is a retrospective case series summarizing the authors' experience with this medication. In a 20-patient case series from an institutional review board-approved retrospective chart review, the tolerability and efficacy of lamotrigine was evaluated for the management of agitated and aggressive behaviors in nursing home patients with a range of psychiatric and medical diagnoses. Nineteen of the elderly nursing home patients tolerated lamotrigine treatment, and 18 showed modest clinical improvement. These results support the authors' belief that controlled clinical investigations of this medication should be performed.

Original languageEnglish
Pages (from-to)8-11
Number of pages4
JournalJournal of Geriatric Psychiatry and Neurology
Issue number1
Publication statusPublished - 1 Mar 2005



  • Aggression
  • Agitation
  • Dementia
  • Geriatrics
  • Lamotrigine

ASJC Scopus subject areas

  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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