Tolerability and effectiveness of lamotrigine in complex elderly patients

Jasdeep S. Aulakh, James W. Hawkins, Herman S. Athwal, Javaid Sheikh, Jerome Yesavage, Jared R. Tinklenberg

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

There is paucity of medical literature on the use of lamotrigine in elderly patients who have behavior problems and diverse psychiatric syndromes. This article is a retrospective case series summarizing the authors' experience with this medication. In a 20-patient case series from an institutional review board-approved retrospective chart review, the tolerability and efficacy of lamotrigine was evaluated for the management of agitated and aggressive behaviors in nursing home patients with a range of psychiatric and medical diagnoses. Nineteen of the elderly nursing home patients tolerated lamotrigine treatment, and 18 showed modest clinical improvement. These results support the authors' belief that controlled clinical investigations of this medication should be performed.

Original languageEnglish
Pages (from-to)8-11
Number of pages4
JournalJournal of Geriatric Psychiatry and Neurology
Volume18
Issue number1
DOIs
Publication statusPublished - Mar 2005
Externally publishedYes

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Nursing Homes
Research Ethics Committees
Mental Disorders
Psychiatry
lamotrigine
Therapeutics
Problem Behavior

Keywords

  • Aggression
  • Agitation
  • Dementia
  • Geriatrics
  • Lamotrigine

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Geriatrics and Gerontology
  • Neuroscience(all)

Cite this

Tolerability and effectiveness of lamotrigine in complex elderly patients. / Aulakh, Jasdeep S.; Hawkins, James W.; Athwal, Herman S.; Sheikh, Javaid; Yesavage, Jerome; Tinklenberg, Jared R.

In: Journal of Geriatric Psychiatry and Neurology, Vol. 18, No. 1, 03.2005, p. 8-11.

Research output: Contribution to journalReview article

Aulakh, Jasdeep S. ; Hawkins, James W. ; Athwal, Herman S. ; Sheikh, Javaid ; Yesavage, Jerome ; Tinklenberg, Jared R. / Tolerability and effectiveness of lamotrigine in complex elderly patients. In: Journal of Geriatric Psychiatry and Neurology. 2005 ; Vol. 18, No. 1. pp. 8-11.
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