The molecular aspects of elastin gene expression

J. M. Davidson, R. G. Crystal

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This report summarizes recent advances in the understanding of the molecular mechansims which provide the basis for the regulation of elastin synthesis. Methods are available for the direct quantitation of elastin messenger RNA activity and absolute levels of elastin messenger RNA. Current evidence suggests, that at least some systems, regulation of elastin synthesis primarily occurs at a pretranslational level. Recent advances in the cloning of elastin cDNA and elastin genes will permit the determination of elastin and elastin gene primary structure. These cloned elastin genes will also provide useful probes for the further analysis of the control of elastin gene expression in development and disease states.

Original languageEnglish
Pages (from-to)133-137
Number of pages5
JournalJournal of Investigative Dermatology
Volume79
Issue numberSuppl. 1
DOIs
Publication statusPublished - 1 Jan 1982

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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