The future of immunoimaging - Deeper, bigger, more precise, and definitively more colorful

Jianyong Tang, Nicholas J. Van Panhuys, Wolfgang Kastenmüller, Ronald N. Germain

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Immune cells are thoroughbreds, moving farther and faster and surveying more diverse tissue space than their nonhematopoietic brethren. Intravital 2-photon microscopy has provided insights into the movements and interactions of many immune cell types in diverse tissues, but more information is needed to link such analyses of dynamic cell behavior to function. Here, we describe additional methods whose application promises to extend our vision, allowing more complete, multiscale dissection of how immune cell positioning and movement are linked to system state, host defense, and disease. Published 2013. This is a US Government work and is in the public domain in the USA.

Original languageEnglish
Pages (from-to)1407-1412
Number of pages6
JournalEuropean Journal of Immunology
Volume43
Issue number6
DOIs
Publication statusPublished - Jun 2013
Externally publishedYes

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Keywords

  • 2-photon
  • Dynamic
  • Imaging
  • Immune responses
  • Multicolor

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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