The evolution of eccrine sweat gland research towards developing a model for human sweat gland function

Research output: Contribution to journalReview article

2 Citations (Scopus)


For several decades now, researchers, professional bodies, governments, and journals such as the journal of Experimental Dermatology have worked to reduce the number of animals used in experimentation. This review centres on investigations into how human sweat glands produce sweat and how that research has evolved over the years. It is hoped that this review will show that as methodologies advanced, sweat gland research has come to rely less and less on a variety of animal models as investigative tools and information is being primarily obtained through human and mouse material, with a view to further reductions in using animal models.

Original languageEnglish
Pages (from-to)544-550
Number of pages7
JournalExperimental Dermatology
Issue number5
Publication statusPublished - 1 May 2018



  • human eccrine sweat glands

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology

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