The early antitumor immune response is necessary for tumor growth: Re-visiting prehn's hypothesis in the human melanoma system

Giorgio Parmiani, Cristina Maccalli

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Early events responsible of tumor growth in patients with a normal immune system are poorly understood. Here, we discuss, in the context of human melanoma, the Prehn hypothesis according to which a weak antitumor immune response may be required for tumor growth before weakly or nonimmunogenic tumor cell subpopulations are selected by the immune system.

Original languageEnglish
Pages (from-to)930-934
Number of pages5
JournalOncoImmunology
Volume1
Issue number6
DOIs
Publication statusPublished - 2012
Externally publishedYes

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Melanoma
Immune System
Growth
Neoplasms

Keywords

  • Cancer immunosurveillance
  • Early tumor growth
  • Immune escape
  • Melanoma
  • Microenvironment
  • Tumor antigens

ASJC Scopus subject areas

  • Immunology and Allergy
  • Oncology
  • Immunology

Cite this

The early antitumor immune response is necessary for tumor growth : Re-visiting prehn's hypothesis in the human melanoma system. / Parmiani, Giorgio; Maccalli, Cristina.

In: OncoImmunology, Vol. 1, No. 6, 2012, p. 930-934.

Research output: Contribution to journalArticle

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