The association between adiposity, mental well-being, and quality of life in extreme obesity

Alison C. Jagielski, Adrian Brown, Marzieh Hosseini-Araghi, G. Neil Thomas, Shahrad Taheri

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objectives: To explore the cross-sectional association between adiposity, mental well-being, and quality of life in extreme obese individuals entering a UK specialist weight management service prior to treatment commencement. Methods: The sample comprised 263 extreme obese individuals who were referred to the service as a result of having a body mass index (BMI) ≥40 kg/m 2 or ≥35 kg/m2 with a co-morbid health condition. In a retrospective analysis, routinely collected baseline clinical examination data and self-report questionnaires (Impact of Weight on Quality of Life: IWQOL-Lite, EQ5D-3L, and Hospital Anxiety and Depression Scale: HADS) were analysed to examine the cross-sectional association between adiposity and quality of life. Results: The sample was predominantly female (74.8%) with mean BMI 47.0±7.9 kg/m2. Increasing adiposity was significantly negatively associated with quality of life, with an increase of 1 BMI unit associated with decreases of 1.93 in physical function (95% CI -2.86 - -1.00, p<0.001), 1.62 in self-esteem (95% CI -2.67 - -0.57, p<0.05), 2.69 in public distress (95% CI -3.75 - -1.62, p<0.001), 1.33 in work (95% CI -2.63 - -0.02, p<0.05), and 1.79 in total IWQOL-Lite scores (95% CI -2.65 - -0.93, p<0.001). Adiposity was associated with significantly increased risk of problems in mobility (OR = 3.44, 95% CI 1.47-8.05), and performing usual activities (OR = 2.45, 95% CI 1.10-5.46) in highest relative to lowest BMI tertile. The prevalence of experience of symptoms of anxiety (70.3%) and depression (66.2%) as measured by HADS was consistently high. Conclusions: We identified a high prevalence of psychological co-morbidity, including widespread experience of symptoms of anxiety and depressive disorders and reduced quality of life among these extreme obese individuals seeking weight management treatment. Clinical implications include the need for the incorporation of strategies to improve mental well-being into multi-disciplinary weight management interventions.

Original languageEnglish
Article numbere92859
JournalPLoS One
Volume9
Issue number3
DOIs
Publication statusPublished - 26 Mar 2014
Externally publishedYes

Fingerprint

Adiposity
adiposity
quality of life
obesity
Obesity
Quality of Life
body mass index
Body Mass Index
weight control
anxiety
Weights and Measures
Anxiety
Depression
self-esteem
Health
Depressive Disorder
distress
Anxiety Disorders
Self Concept
clinical examination

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

The association between adiposity, mental well-being, and quality of life in extreme obesity. / Jagielski, Alison C.; Brown, Adrian; Hosseini-Araghi, Marzieh; Thomas, G. Neil; Taheri, Shahrad.

In: PLoS One, Vol. 9, No. 3, e92859, 26.03.2014.

Research output: Contribution to journalArticle

Jagielski, Alison C. ; Brown, Adrian ; Hosseini-Araghi, Marzieh ; Thomas, G. Neil ; Taheri, Shahrad. / The association between adiposity, mental well-being, and quality of life in extreme obesity. In: PLoS One. 2014 ; Vol. 9, No. 3.
@article{433dd4057b0b43f8af66ba2e1a195e27,
title = "The association between adiposity, mental well-being, and quality of life in extreme obesity",
abstract = "Objectives: To explore the cross-sectional association between adiposity, mental well-being, and quality of life in extreme obese individuals entering a UK specialist weight management service prior to treatment commencement. Methods: The sample comprised 263 extreme obese individuals who were referred to the service as a result of having a body mass index (BMI) ≥40 kg/m 2 or ≥35 kg/m2 with a co-morbid health condition. In a retrospective analysis, routinely collected baseline clinical examination data and self-report questionnaires (Impact of Weight on Quality of Life: IWQOL-Lite, EQ5D-3L, and Hospital Anxiety and Depression Scale: HADS) were analysed to examine the cross-sectional association between adiposity and quality of life. Results: The sample was predominantly female (74.8{\%}) with mean BMI 47.0±7.9 kg/m2. Increasing adiposity was significantly negatively associated with quality of life, with an increase of 1 BMI unit associated with decreases of 1.93 in physical function (95{\%} CI -2.86 - -1.00, p<0.001), 1.62 in self-esteem (95{\%} CI -2.67 - -0.57, p<0.05), 2.69 in public distress (95{\%} CI -3.75 - -1.62, p<0.001), 1.33 in work (95{\%} CI -2.63 - -0.02, p<0.05), and 1.79 in total IWQOL-Lite scores (95{\%} CI -2.65 - -0.93, p<0.001). Adiposity was associated with significantly increased risk of problems in mobility (OR = 3.44, 95{\%} CI 1.47-8.05), and performing usual activities (OR = 2.45, 95{\%} CI 1.10-5.46) in highest relative to lowest BMI tertile. The prevalence of experience of symptoms of anxiety (70.3{\%}) and depression (66.2{\%}) as measured by HADS was consistently high. Conclusions: We identified a high prevalence of psychological co-morbidity, including widespread experience of symptoms of anxiety and depressive disorders and reduced quality of life among these extreme obese individuals seeking weight management treatment. Clinical implications include the need for the incorporation of strategies to improve mental well-being into multi-disciplinary weight management interventions.",
author = "Jagielski, {Alison C.} and Adrian Brown and Marzieh Hosseini-Araghi and Thomas, {G. Neil} and Shahrad Taheri",
year = "2014",
month = "3",
day = "26",
doi = "10.1371/journal.pone.0092859",
language = "English",
volume = "9",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "3",

}

TY - JOUR

T1 - The association between adiposity, mental well-being, and quality of life in extreme obesity

AU - Jagielski, Alison C.

AU - Brown, Adrian

AU - Hosseini-Araghi, Marzieh

AU - Thomas, G. Neil

AU - Taheri, Shahrad

PY - 2014/3/26

Y1 - 2014/3/26

N2 - Objectives: To explore the cross-sectional association between adiposity, mental well-being, and quality of life in extreme obese individuals entering a UK specialist weight management service prior to treatment commencement. Methods: The sample comprised 263 extreme obese individuals who were referred to the service as a result of having a body mass index (BMI) ≥40 kg/m 2 or ≥35 kg/m2 with a co-morbid health condition. In a retrospective analysis, routinely collected baseline clinical examination data and self-report questionnaires (Impact of Weight on Quality of Life: IWQOL-Lite, EQ5D-3L, and Hospital Anxiety and Depression Scale: HADS) were analysed to examine the cross-sectional association between adiposity and quality of life. Results: The sample was predominantly female (74.8%) with mean BMI 47.0±7.9 kg/m2. Increasing adiposity was significantly negatively associated with quality of life, with an increase of 1 BMI unit associated with decreases of 1.93 in physical function (95% CI -2.86 - -1.00, p<0.001), 1.62 in self-esteem (95% CI -2.67 - -0.57, p<0.05), 2.69 in public distress (95% CI -3.75 - -1.62, p<0.001), 1.33 in work (95% CI -2.63 - -0.02, p<0.05), and 1.79 in total IWQOL-Lite scores (95% CI -2.65 - -0.93, p<0.001). Adiposity was associated with significantly increased risk of problems in mobility (OR = 3.44, 95% CI 1.47-8.05), and performing usual activities (OR = 2.45, 95% CI 1.10-5.46) in highest relative to lowest BMI tertile. The prevalence of experience of symptoms of anxiety (70.3%) and depression (66.2%) as measured by HADS was consistently high. Conclusions: We identified a high prevalence of psychological co-morbidity, including widespread experience of symptoms of anxiety and depressive disorders and reduced quality of life among these extreme obese individuals seeking weight management treatment. Clinical implications include the need for the incorporation of strategies to improve mental well-being into multi-disciplinary weight management interventions.

AB - Objectives: To explore the cross-sectional association between adiposity, mental well-being, and quality of life in extreme obese individuals entering a UK specialist weight management service prior to treatment commencement. Methods: The sample comprised 263 extreme obese individuals who were referred to the service as a result of having a body mass index (BMI) ≥40 kg/m 2 or ≥35 kg/m2 with a co-morbid health condition. In a retrospective analysis, routinely collected baseline clinical examination data and self-report questionnaires (Impact of Weight on Quality of Life: IWQOL-Lite, EQ5D-3L, and Hospital Anxiety and Depression Scale: HADS) were analysed to examine the cross-sectional association between adiposity and quality of life. Results: The sample was predominantly female (74.8%) with mean BMI 47.0±7.9 kg/m2. Increasing adiposity was significantly negatively associated with quality of life, with an increase of 1 BMI unit associated with decreases of 1.93 in physical function (95% CI -2.86 - -1.00, p<0.001), 1.62 in self-esteem (95% CI -2.67 - -0.57, p<0.05), 2.69 in public distress (95% CI -3.75 - -1.62, p<0.001), 1.33 in work (95% CI -2.63 - -0.02, p<0.05), and 1.79 in total IWQOL-Lite scores (95% CI -2.65 - -0.93, p<0.001). Adiposity was associated with significantly increased risk of problems in mobility (OR = 3.44, 95% CI 1.47-8.05), and performing usual activities (OR = 2.45, 95% CI 1.10-5.46) in highest relative to lowest BMI tertile. The prevalence of experience of symptoms of anxiety (70.3%) and depression (66.2%) as measured by HADS was consistently high. Conclusions: We identified a high prevalence of psychological co-morbidity, including widespread experience of symptoms of anxiety and depressive disorders and reduced quality of life among these extreme obese individuals seeking weight management treatment. Clinical implications include the need for the incorporation of strategies to improve mental well-being into multi-disciplinary weight management interventions.

UR - http://www.scopus.com/inward/record.url?scp=84899790628&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899790628&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0092859

DO - 10.1371/journal.pone.0092859

M3 - Article

VL - 9

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 3

M1 - e92859

ER -