The A, C, G, and T of genome assembly

Bilal Wajid, Muhammad U. Sohail, Ali R. Ekti, Erchin Serpedin

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.

Original languageEnglish
Article number6329217
JournalBioMed Research International
Volume2016
DOIs
Publication statusPublished - 2016
Externally publishedYes

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ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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