Synthesis and calcium channel antagonist activity of dialkyl 4-(dihydropyridinyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarbox ylates

L. Dagnino, M. C. Li-Kwong-Ken, H. Wynn, M. W. Wolowyk, Christopher Triggle, E. E. Knaus

Research output: Contribution to journalArticle

51 Citations (Scopus)
Original languageEnglish
Pages (from-to)640-646
Number of pages7
JournalJournal of Medicinal Chemistry
Volume30
Issue number4
DOIs
Publication statusPublished - 1987
Externally publishedYes

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Pyridines
Dicarboxylic Acids
Calcium Channel Blockers
Muscarinic Receptors
Structure-Activity Relationship
Muscle Contraction
Smooth Muscle
Guinea Pigs
Esters
Dihydropyridines
Nitrendipine
Carbamates
Cholinergic Agents
Nitrogen
Calcium

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

Cite this

Synthesis and calcium channel antagonist activity of dialkyl 4-(dihydropyridinyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarbox ylates. / Dagnino, L.; Li-Kwong-Ken, M. C.; Wynn, H.; Wolowyk, M. W.; Triggle, Christopher; Knaus, E. E.

In: Journal of Medicinal Chemistry, Vol. 30, No. 4, 1987, p. 640-646.

Research output: Contribution to journalArticle

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AU - Wolowyk, M. W.

AU - Triggle, Christopher

AU - Knaus, E. E.

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