Synthesis and calcium channel antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pyridinyl)3,5-pyridinedicarboxylates

Christopher Triggle, M. C. Li-Kwong Ken, M. W. Wolowyk, M. C. Li-Kwong-Ken, H. Wynn, C. R. Triggle, E. E. Knaus

Research output: Contribution to journalArticle

52 Citations (Scopus)
Original languageEnglish
Pages (from-to)2524-2529
Number of pages6
JournalJournal of Medicinal Chemistry
Volume29
Issue number12
DOIs
Publication statusPublished - 1986
Externally publishedYes

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Pyridines
Calcium Channel Blockers
Structure-Activity Relationship
Muscle Contraction
Ileum
Smooth Muscle
Guinea Pigs
Esters
Calcium
Acetoacetates
Ammonium Hydroxide
Nitrendipine
Muscarinic Receptors
Cholinergic Agents

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

Cite this

Synthesis and calcium channel antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pyridinyl)3,5-pyridinedicarboxylates. / Triggle, Christopher; Li-Kwong Ken, M. C.; Wolowyk, M. W.; Li-Kwong-Ken, M. C.; Wynn, H.; Triggle, C. R.; Knaus, E. E.

In: Journal of Medicinal Chemistry, Vol. 29, No. 12, 1986, p. 2524-2529.

Research output: Contribution to journalArticle

Triggle, Christopher ; Li-Kwong Ken, M. C. ; Wolowyk, M. W. ; Li-Kwong-Ken, M. C. ; Wynn, H. ; Triggle, C. R. ; Knaus, E. E. / Synthesis and calcium channel antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pyridinyl)3,5-pyridinedicarboxylates. In: Journal of Medicinal Chemistry. 1986 ; Vol. 29, No. 12. pp. 2524-2529.
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