Specific change in spectral power of fetal heart rate variability related to fetal acidemia during labor: Comparison between preterm and term fetuses

Ji Young Kwon, In Yang Park, Jong Chul Shin, Juhee Song, Reza Tafreshi, Jongil Lim

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background: Spectral analysis of fetal heart rate (FHR) variability is a useful method to assess fetal condition. There have been several studies involving the change in spectral power related to fetal acidemia, but the results have been inconsistent. Aims: To determine the change in spectral power related to fetal umbilical arterial pH at birth, dividing cases into preterm (31-36. weeks) and term (≥ 37. weeks) gestations. Study design: Case-control study. The 514 cases of deliveries were divided into a low-pH group (an umbilical arterial pH < 7.2) and a control group (pH ≥ 7.2). Subjects: FHR recorded on cardiotocography during the last 2. h of labor. Outcome measures: The spectral powers in various bands of FHR variability. Results: In preterm fetuses, the total, low (LF), and movement (MF) frequency spectral powers and LF/HF ratio were significantly lower in the low-pH group than the control group (all P< 0.05). In contrast, in term fetuses, the total frequency, LF, and MF powers were significantly higher in the low-pH group than the control group (all P< 0.05). The area under the receiver operating characteristic of LF power to detect a low pH at birth was 0.794 in preterm fetuses and 0.595 in term fetuses. The specificity was 86.8% and 93.3% in preterm and term fetuses, respectively. Conclusions: The changes in spectral power responding to a low pH are different between term and preterm fetuses. Spectral analysis of FHR variability may be useful fetal monitoring for early detection of fetal acidemia.

Original languageEnglish
Pages (from-to)203-207
Number of pages5
JournalEarly Human Development
Volume88
Issue number4
DOIs
Publication statusPublished - Apr 2012

Fingerprint

Fetal Heart Rate
Fetus
Umbilicus
Control Groups
Parturition
Cardiotocography
Fetal Monitoring
ROC Curve
Case-Control Studies
Outcome Assessment (Health Care)
Pregnancy

Keywords

  • Cardiotocography
  • Fetal acidemia
  • Heart rate variability
  • Spectral analysis
  • Umbilical arterial low pH

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

Specific change in spectral power of fetal heart rate variability related to fetal acidemia during labor : Comparison between preterm and term fetuses. / Kwon, Ji Young; Park, In Yang; Shin, Jong Chul; Song, Juhee; Tafreshi, Reza; Lim, Jongil.

In: Early Human Development, Vol. 88, No. 4, 04.2012, p. 203-207.

Research output: Contribution to journalArticle

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abstract = "Background: Spectral analysis of fetal heart rate (FHR) variability is a useful method to assess fetal condition. There have been several studies involving the change in spectral power related to fetal acidemia, but the results have been inconsistent. Aims: To determine the change in spectral power related to fetal umbilical arterial pH at birth, dividing cases into preterm (31-36. weeks) and term (≥ 37. weeks) gestations. Study design: Case-control study. The 514 cases of deliveries were divided into a low-pH group (an umbilical arterial pH < 7.2) and a control group (pH ≥ 7.2). Subjects: FHR recorded on cardiotocography during the last 2. h of labor. Outcome measures: The spectral powers in various bands of FHR variability. Results: In preterm fetuses, the total, low (LF), and movement (MF) frequency spectral powers and LF/HF ratio were significantly lower in the low-pH group than the control group (all P< 0.05). In contrast, in term fetuses, the total frequency, LF, and MF powers were significantly higher in the low-pH group than the control group (all P< 0.05). The area under the receiver operating characteristic of LF power to detect a low pH at birth was 0.794 in preterm fetuses and 0.595 in term fetuses. The specificity was 86.8{\%} and 93.3{\%} in preterm and term fetuses, respectively. Conclusions: The changes in spectral power responding to a low pH are different between term and preterm fetuses. Spectral analysis of FHR variability may be useful fetal monitoring for early detection of fetal acidemia.",
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N2 - Background: Spectral analysis of fetal heart rate (FHR) variability is a useful method to assess fetal condition. There have been several studies involving the change in spectral power related to fetal acidemia, but the results have been inconsistent. Aims: To determine the change in spectral power related to fetal umbilical arterial pH at birth, dividing cases into preterm (31-36. weeks) and term (≥ 37. weeks) gestations. Study design: Case-control study. The 514 cases of deliveries were divided into a low-pH group (an umbilical arterial pH < 7.2) and a control group (pH ≥ 7.2). Subjects: FHR recorded on cardiotocography during the last 2. h of labor. Outcome measures: The spectral powers in various bands of FHR variability. Results: In preterm fetuses, the total, low (LF), and movement (MF) frequency spectral powers and LF/HF ratio were significantly lower in the low-pH group than the control group (all P< 0.05). In contrast, in term fetuses, the total frequency, LF, and MF powers were significantly higher in the low-pH group than the control group (all P< 0.05). The area under the receiver operating characteristic of LF power to detect a low pH at birth was 0.794 in preterm fetuses and 0.595 in term fetuses. The specificity was 86.8% and 93.3% in preterm and term fetuses, respectively. Conclusions: The changes in spectral power responding to a low pH are different between term and preterm fetuses. Spectral analysis of FHR variability may be useful fetal monitoring for early detection of fetal acidemia.

AB - Background: Spectral analysis of fetal heart rate (FHR) variability is a useful method to assess fetal condition. There have been several studies involving the change in spectral power related to fetal acidemia, but the results have been inconsistent. Aims: To determine the change in spectral power related to fetal umbilical arterial pH at birth, dividing cases into preterm (31-36. weeks) and term (≥ 37. weeks) gestations. Study design: Case-control study. The 514 cases of deliveries were divided into a low-pH group (an umbilical arterial pH < 7.2) and a control group (pH ≥ 7.2). Subjects: FHR recorded on cardiotocography during the last 2. h of labor. Outcome measures: The spectral powers in various bands of FHR variability. Results: In preterm fetuses, the total, low (LF), and movement (MF) frequency spectral powers and LF/HF ratio were significantly lower in the low-pH group than the control group (all P< 0.05). In contrast, in term fetuses, the total frequency, LF, and MF powers were significantly higher in the low-pH group than the control group (all P< 0.05). The area under the receiver operating characteristic of LF power to detect a low pH at birth was 0.794 in preterm fetuses and 0.595 in term fetuses. The specificity was 86.8% and 93.3% in preterm and term fetuses, respectively. Conclusions: The changes in spectral power responding to a low pH are different between term and preterm fetuses. Spectral analysis of FHR variability may be useful fetal monitoring for early detection of fetal acidemia.

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