Spatial Orientation and Morphology of the Pulmonary Artery: Relevance to Optimising Design and Positioning of a Continuous Pressure Monitoring Device

Su Lin Lee, Heba Aguib, Julien Chapron, Reza Bahmanyar, Alessandro Borghi, Olive Murphy, Chris McLeod, Ahmed ElGuindy, Magdi Yacoub

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Abstract

    Personalised treatment of heart disease requires an understanding of the patient-specific characteristics, which can vary over time. A newly developed implantable surface acoustic wave pressure sensor, capable of continuous monitoring of the left ventricle filling pressure, is a novel device for personalised management of patients with heart disease. However, a one-size-fits-all approach to device sizing will affect its positioning within the pulmonary artery and its relationship to the interrogating device on the chest wall on a patient-specific level. In this paper, we analyse the spatial orientation and morphology of the pulmonary artery and its main branches in patients who could benefit from the device and normal controls. The results could optimise the design of the sensor, its stent, and importantly its placement, ensuring long-term monitoring in patient groups.

    Original languageEnglish
    Pages (from-to)239-248
    Number of pages10
    JournalJournal of Cardiovascular Translational Research
    Volume9
    Issue number3
    DOIs
    Publication statusPublished - 1 Jun 2016

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    Keywords

    • Device design
    • Morphology
    • Orientation
    • Pressure monitoring
    • Pulmonary artery

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine
    • Genetics
    • Genetics(clinical)
    • Molecular Medicine
    • Pharmaceutical Science

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