Smell–taste dysfunctions in extreme weight/eating conditions

analysis of hormonal and psychological interactions

Fernando Fernández-Aranda, Zaida Agüera, Jose C. Fernández-García, Lourdes Garrido-Sanchez, Juan Alcaide-Torres, Francisco J. Tinahones, Cristina Giner-Bartolomé, Rosa M. Baños, Cristina Botella, Ausias Cebolla, Rafael de la Torre, Jose M. Fernández-Real, Francisco J. Ortega, Gema Frühbeck, Javier Gómez-Ambrosi, Roser Granero, Mohamed A. Islam, Susana Jiménez-Murcia, Salomé Tárrega, José M. Menchón & 5 others Ana B. Fagundo, Carolina Sancho, Xavier P. Estivill, Janet Treasure, Felipe F. Casanueva

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

(1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through “Sniffin’ Sticks” and “Taste Strips,” respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.

Original languageEnglish
Pages (from-to)256-267
Number of pages12
JournalEndocrine
Volume51
Issue number2
DOIs
Publication statusPublished - 1 Feb 2016
Externally publishedYes

Fingerprint

Smell
Eating
Ghrelin
Psychology
Weights and Measures
Anorexia Nervosa
Feeding Behavior
Body Mass Index
Peptide YY
Cholecystokinin
Gastrointestinal Tract
Stomach
Obesity
Hormones
Equipment and Supplies
Peptides

Keywords

  • Anorexia nervosa
  • Emotional eating
  • Ghrelin
  • Obesity
  • Smell
  • Taste

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Fernández-Aranda, F., Agüera, Z., Fernández-García, J. C., Garrido-Sanchez, L., Alcaide-Torres, J., Tinahones, F. J., ... Casanueva, F. F. (2016). Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions. Endocrine, 51(2), 256-267. https://doi.org/10.1007/s12020-015-0684-9

Smell–taste dysfunctions in extreme weight/eating conditions : analysis of hormonal and psychological interactions. / Fernández-Aranda, Fernando; Agüera, Zaida; Fernández-García, Jose C.; Garrido-Sanchez, Lourdes; Alcaide-Torres, Juan; Tinahones, Francisco J.; Giner-Bartolomé, Cristina; Baños, Rosa M.; Botella, Cristina; Cebolla, Ausias; de la Torre, Rafael; Fernández-Real, Jose M.; Ortega, Francisco J.; Frühbeck, Gema; Gómez-Ambrosi, Javier; Granero, Roser; Islam, Mohamed A.; Jiménez-Murcia, Susana; Tárrega, Salomé; Menchón, José M.; Fagundo, Ana B.; Sancho, Carolina; Estivill, Xavier P.; Treasure, Janet; Casanueva, Felipe F.

In: Endocrine, Vol. 51, No. 2, 01.02.2016, p. 256-267.

Research output: Contribution to journalArticle

Fernández-Aranda, F, Agüera, Z, Fernández-García, JC, Garrido-Sanchez, L, Alcaide-Torres, J, Tinahones, FJ, Giner-Bartolomé, C, Baños, RM, Botella, C, Cebolla, A, de la Torre, R, Fernández-Real, JM, Ortega, FJ, Frühbeck, G, Gómez-Ambrosi, J, Granero, R, Islam, MA, Jiménez-Murcia, S, Tárrega, S, Menchón, JM, Fagundo, AB, Sancho, C, Estivill, XP, Treasure, J & Casanueva, FF 2016, 'Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions', Endocrine, vol. 51, no. 2, pp. 256-267. https://doi.org/10.1007/s12020-015-0684-9
Fernández-Aranda F, Agüera Z, Fernández-García JC, Garrido-Sanchez L, Alcaide-Torres J, Tinahones FJ et al. Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions. Endocrine. 2016 Feb 1;51(2):256-267. https://doi.org/10.1007/s12020-015-0684-9
Fernández-Aranda, Fernando ; Agüera, Zaida ; Fernández-García, Jose C. ; Garrido-Sanchez, Lourdes ; Alcaide-Torres, Juan ; Tinahones, Francisco J. ; Giner-Bartolomé, Cristina ; Baños, Rosa M. ; Botella, Cristina ; Cebolla, Ausias ; de la Torre, Rafael ; Fernández-Real, Jose M. ; Ortega, Francisco J. ; Frühbeck, Gema ; Gómez-Ambrosi, Javier ; Granero, Roser ; Islam, Mohamed A. ; Jiménez-Murcia, Susana ; Tárrega, Salomé ; Menchón, José M. ; Fagundo, Ana B. ; Sancho, Carolina ; Estivill, Xavier P. ; Treasure, Janet ; Casanueva, Felipe F. / Smell–taste dysfunctions in extreme weight/eating conditions : analysis of hormonal and psychological interactions. In: Endocrine. 2016 ; Vol. 51, No. 2. pp. 256-267.
@article{887ffbc71dcf4b908921d5533bc3e94a,
title = "Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions",
abstract = "(1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through “Sniffin’ Sticks” and “Taste Strips,” respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 {\%} in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.",
keywords = "Anorexia nervosa, Emotional eating, Ghrelin, Obesity, Smell, Taste",
author = "Fernando Fern{\'a}ndez-Aranda and Zaida Ag{\"u}era and Fern{\'a}ndez-Garc{\'i}a, {Jose C.} and Lourdes Garrido-Sanchez and Juan Alcaide-Torres and Tinahones, {Francisco J.} and Cristina Giner-Bartolom{\'e} and Ba{\~n}os, {Rosa M.} and Cristina Botella and Ausias Cebolla and {de la Torre}, Rafael and Fern{\'a}ndez-Real, {Jose M.} and Ortega, {Francisco J.} and Gema Fr{\"u}hbeck and Javier G{\'o}mez-Ambrosi and Roser Granero and Islam, {Mohamed A.} and Susana Jim{\'e}nez-Murcia and Salom{\'e} T{\'a}rrega and Mench{\'o}n, {Jos{\'e} M.} and Fagundo, {Ana B.} and Carolina Sancho and Estivill, {Xavier P.} and Janet Treasure and Casanueva, {Felipe F.}",
year = "2016",
month = "2",
day = "1",
doi = "10.1007/s12020-015-0684-9",
language = "English",
volume = "51",
pages = "256--267",
journal = "Endocrine",
issn = "1355-008X",
publisher = "Humana Press",
number = "2",

}

TY - JOUR

T1 - Smell–taste dysfunctions in extreme weight/eating conditions

T2 - analysis of hormonal and psychological interactions

AU - Fernández-Aranda, Fernando

AU - Agüera, Zaida

AU - Fernández-García, Jose C.

AU - Garrido-Sanchez, Lourdes

AU - Alcaide-Torres, Juan

AU - Tinahones, Francisco J.

AU - Giner-Bartolomé, Cristina

AU - Baños, Rosa M.

AU - Botella, Cristina

AU - Cebolla, Ausias

AU - de la Torre, Rafael

AU - Fernández-Real, Jose M.

AU - Ortega, Francisco J.

AU - Frühbeck, Gema

AU - Gómez-Ambrosi, Javier

AU - Granero, Roser

AU - Islam, Mohamed A.

AU - Jiménez-Murcia, Susana

AU - Tárrega, Salomé

AU - Menchón, José M.

AU - Fagundo, Ana B.

AU - Sancho, Carolina

AU - Estivill, Xavier P.

AU - Treasure, Janet

AU - Casanueva, Felipe F.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - (1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through “Sniffin’ Sticks” and “Taste Strips,” respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.

AB - (1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through “Sniffin’ Sticks” and “Taste Strips,” respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.

KW - Anorexia nervosa

KW - Emotional eating

KW - Ghrelin

KW - Obesity

KW - Smell

KW - Taste

UR - http://www.scopus.com/inward/record.url?scp=84956962988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84956962988&partnerID=8YFLogxK

U2 - 10.1007/s12020-015-0684-9

DO - 10.1007/s12020-015-0684-9

M3 - Article

VL - 51

SP - 256

EP - 267

JO - Endocrine

JF - Endocrine

SN - 1355-008X

IS - 2

ER -