Abstract
The general decline in sleep duration during the past 25 years has made suboptimal sleep quality a more common phenomenon (Jean-Louis et al., Biol Psychiatry 47:921-927, 2000). Reasons for reduced sleep include increased working hours, shift work and more time spent watching the television and exploring the internet (Bonnet and Arand, Sleep 18:908-911, 1995). Disruptions in sleep parameters have been related to a variety of health outcomes. Animal studies have shown that extreme levels of sleep deprivation are highly detrimental. Rats subjected to total sleep deprivation for up to 21 days displayed global deterioration ultimately resulting in death (Everson and Wehr, Am J Physiol 264:R376-R387, 1993). Epidemiological studies in humans have indicated that both short- and long-sleep duration is associated with increased morbidity and mortality. Most notably, a study of 1.1 million participants in the American Cancer Prevention Society demonstrated that survival was optimal in people who slept 7 h per night. Sleep durations of 8.5 h or more, or less than 4.5 h were significantly associated with increased mortality as well as higher body mass index (BMI) scores (Kripke et al., Arch Gen Psychiatry 59:131-136, 2002).
| Original language | English |
|---|---|
| Title of host publication | Immunosenescence: Psychosocial and Behavioral Determinants |
| Publisher | Springer New York |
| Pages | 201-219 |
| Number of pages | 19 |
| Volume | 9781461447764 |
| ISBN (Electronic) | 9781461447764 |
| ISBN (Print) | 1461447755, 9781461447757 |
| DOIs | |
| Publication status | Published - 1 May 2013 |
| Externally published | Yes |
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Keywords
- Ageing
- Immunesenescence
- Sleep
- Sleep quality
ASJC Scopus subject areas
- Medicine(all)
- Immunology and Microbiology(all)
Cite this
Sleep and immunity in older age. / Hampson, Peter; Rossi, Alessandra; Arora, Teresa; Lord, Janet M.; Taheri, Shahrad.
Immunosenescence: Psychosocial and Behavioral Determinants. Vol. 9781461447764 Springer New York, 2013. p. 201-219.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Sleep and immunity in older age
AU - Hampson, Peter
AU - Rossi, Alessandra
AU - Arora, Teresa
AU - Lord, Janet M.
AU - Taheri, Shahrad
PY - 2013/5/1
Y1 - 2013/5/1
N2 - The general decline in sleep duration during the past 25 years has made suboptimal sleep quality a more common phenomenon (Jean-Louis et al., Biol Psychiatry 47:921-927, 2000). Reasons for reduced sleep include increased working hours, shift work and more time spent watching the television and exploring the internet (Bonnet and Arand, Sleep 18:908-911, 1995). Disruptions in sleep parameters have been related to a variety of health outcomes. Animal studies have shown that extreme levels of sleep deprivation are highly detrimental. Rats subjected to total sleep deprivation for up to 21 days displayed global deterioration ultimately resulting in death (Everson and Wehr, Am J Physiol 264:R376-R387, 1993). Epidemiological studies in humans have indicated that both short- and long-sleep duration is associated with increased morbidity and mortality. Most notably, a study of 1.1 million participants in the American Cancer Prevention Society demonstrated that survival was optimal in people who slept 7 h per night. Sleep durations of 8.5 h or more, or less than 4.5 h were significantly associated with increased mortality as well as higher body mass index (BMI) scores (Kripke et al., Arch Gen Psychiatry 59:131-136, 2002).
AB - The general decline in sleep duration during the past 25 years has made suboptimal sleep quality a more common phenomenon (Jean-Louis et al., Biol Psychiatry 47:921-927, 2000). Reasons for reduced sleep include increased working hours, shift work and more time spent watching the television and exploring the internet (Bonnet and Arand, Sleep 18:908-911, 1995). Disruptions in sleep parameters have been related to a variety of health outcomes. Animal studies have shown that extreme levels of sleep deprivation are highly detrimental. Rats subjected to total sleep deprivation for up to 21 days displayed global deterioration ultimately resulting in death (Everson and Wehr, Am J Physiol 264:R376-R387, 1993). Epidemiological studies in humans have indicated that both short- and long-sleep duration is associated with increased morbidity and mortality. Most notably, a study of 1.1 million participants in the American Cancer Prevention Society demonstrated that survival was optimal in people who slept 7 h per night. Sleep durations of 8.5 h or more, or less than 4.5 h were significantly associated with increased mortality as well as higher body mass index (BMI) scores (Kripke et al., Arch Gen Psychiatry 59:131-136, 2002).
KW - Ageing
KW - Immunesenescence
KW - Sleep
KW - Sleep quality
UR - http://www.scopus.com/inward/record.url?scp=84949179492&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84949179492&partnerID=8YFLogxK
U2 - 10.1007/978-1-4614-4776-4_12
DO - 10.1007/978-1-4614-4776-4_12
M3 - Chapter
AN - SCOPUS:84949179492
SN - 1461447755
SN - 9781461447757
VL - 9781461447764
SP - 201
EP - 219
BT - Immunosenescence: Psychosocial and Behavioral Determinants
PB - Springer New York
ER -