Skin Epidermal Thickness and Vascular Density in Type 1 Diabetes

R. A. Malik, J. Metcalfe, A. K. Sharma, J. L. Day, G. Rayman

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Epidermal skin thickness and vascular density were assessed in skin biopsies obtained from the dorsum of the foot in 28 Type 1 diabetic patients and 17 normal control subjects, matched for age. Epidermal skin thickness did not differ significantly between control subjects (74 ± 4 (± SE) μ m) and diabetic patients (78 ± 4 μm). It was not related to the duration of diabetes and presence of complications. Neither small (capillary) nor large (arteriole/venule) vessel densities differed significantly between control subjects (59 ± 6 mm−2 and 19 ± 2 mm−2) and diabetic patients (65 ± 4 mm−2 and 22 ± 3 mm−2). Vessel densities were unrelated to the duration of diabetes and presence of complications. 1992 Diabetes UK

Original languageEnglish
Pages (from-to)263-267
Number of pages5
JournalDiabetic Medicine
Issue number3
Publication statusPublished - Apr 1992



  • Diabetic complications
  • Epidermal skin thickness
  • Vascular density

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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