Routine glutamic acid decarboxylase autoantibody (GADA) testing

Patients' perspective

H. Davies, Sopna Choudhury, S. Brophy, R. Williams

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background. Latent autoimmune diabetes in adults (LADA) is a form of type 1 diabetes which in the UK is often diagnosed and treated as type 2 diabetes (T2D). People with LADA show slow progression to insulin dependence and can be distinguished from T2D by blood tests for glutamic acid decarboxylase autoantibodies (GADA). Aims. This study explores the views and experiences of patients who are newly diagnosed with LADA, with particular reference to (i) routine GADA testing; (ii) whether this diagnosis has any influence on the self-management of their diabetes; and (iii) the information needs of patients newly diagnosed with LADA. Methods. Ten consecutive patients newly diagnosed with LADA (GADA positive) were invited to participate in individual qualitative semi-structured interviews. Their views and experiences were analysed into codes and categories, using a constant comparative method. Findings. Participants supported routine GADA testing in all patients with diabetes because the provision of a correct diagnosis has an empowering effect on patients, as it encourages the consideration of treatment options early on in the condition. Participants preferred to rely on future Hba1c levels and their doctor's opinion to determine a change in treatment to insulin. Some participants had difficulty distinguishing between the different types of diabetes, including LADA. Others needed to ask questions about LADA in addition to written information. Conclusions. Participants were supportive of routine GADA testing, would prefer not to start insulin immediately following a diagnosis of LADA and needed to discuss treatment options with health professionals who were knowledgeable on LADA.

Original languageEnglish
Pages (from-to)176-180
Number of pages5
JournalFamily Practice
Volume25
Issue number3
DOIs
Publication statusPublished - 1 Jun 2008
Externally publishedYes

Fingerprint

Glutamate Decarboxylase
Autoantibodies
Insulin
Type 2 Diabetes Mellitus
Latent Autoimmune Diabetes in Adults
Hematologic Tests
Self Care
Type 1 Diabetes Mellitus
Therapeutics
Interviews
Health

Keywords

  • Latent autoimmune diabetes in adults
  • Patient views
  • Qualitative

ASJC Scopus subject areas

  • Family Practice

Cite this

Routine glutamic acid decarboxylase autoantibody (GADA) testing : Patients' perspective. / Davies, H.; Choudhury, Sopna; Brophy, S.; Williams, R.

In: Family Practice, Vol. 25, No. 3, 01.06.2008, p. 176-180.

Research output: Contribution to journalArticle

Davies, H. ; Choudhury, Sopna ; Brophy, S. ; Williams, R. / Routine glutamic acid decarboxylase autoantibody (GADA) testing : Patients' perspective. In: Family Practice. 2008 ; Vol. 25, No. 3. pp. 176-180.
@article{23bbc5e1198f45ac839e7ca27f4eed70,
title = "Routine glutamic acid decarboxylase autoantibody (GADA) testing: Patients' perspective",
abstract = "Background. Latent autoimmune diabetes in adults (LADA) is a form of type 1 diabetes which in the UK is often diagnosed and treated as type 2 diabetes (T2D). People with LADA show slow progression to insulin dependence and can be distinguished from T2D by blood tests for glutamic acid decarboxylase autoantibodies (GADA). Aims. This study explores the views and experiences of patients who are newly diagnosed with LADA, with particular reference to (i) routine GADA testing; (ii) whether this diagnosis has any influence on the self-management of their diabetes; and (iii) the information needs of patients newly diagnosed with LADA. Methods. Ten consecutive patients newly diagnosed with LADA (GADA positive) were invited to participate in individual qualitative semi-structured interviews. Their views and experiences were analysed into codes and categories, using a constant comparative method. Findings. Participants supported routine GADA testing in all patients with diabetes because the provision of a correct diagnosis has an empowering effect on patients, as it encourages the consideration of treatment options early on in the condition. Participants preferred to rely on future Hba1c levels and their doctor's opinion to determine a change in treatment to insulin. Some participants had difficulty distinguishing between the different types of diabetes, including LADA. Others needed to ask questions about LADA in addition to written information. Conclusions. Participants were supportive of routine GADA testing, would prefer not to start insulin immediately following a diagnosis of LADA and needed to discuss treatment options with health professionals who were knowledgeable on LADA.",
keywords = "Latent autoimmune diabetes in adults, Patient views, Qualitative",
author = "H. Davies and Sopna Choudhury and S. Brophy and R. Williams",
year = "2008",
month = "6",
day = "1",
doi = "10.1093/fampra/cmn016",
language = "English",
volume = "25",
pages = "176--180",
journal = "Family Practice",
issn = "0263-2136",
publisher = "Oxford University Press",
number = "3",

}

TY - JOUR

T1 - Routine glutamic acid decarboxylase autoantibody (GADA) testing

T2 - Patients' perspective

AU - Davies, H.

AU - Choudhury, Sopna

AU - Brophy, S.

AU - Williams, R.

PY - 2008/6/1

Y1 - 2008/6/1

N2 - Background. Latent autoimmune diabetes in adults (LADA) is a form of type 1 diabetes which in the UK is often diagnosed and treated as type 2 diabetes (T2D). People with LADA show slow progression to insulin dependence and can be distinguished from T2D by blood tests for glutamic acid decarboxylase autoantibodies (GADA). Aims. This study explores the views and experiences of patients who are newly diagnosed with LADA, with particular reference to (i) routine GADA testing; (ii) whether this diagnosis has any influence on the self-management of their diabetes; and (iii) the information needs of patients newly diagnosed with LADA. Methods. Ten consecutive patients newly diagnosed with LADA (GADA positive) were invited to participate in individual qualitative semi-structured interviews. Their views and experiences were analysed into codes and categories, using a constant comparative method. Findings. Participants supported routine GADA testing in all patients with diabetes because the provision of a correct diagnosis has an empowering effect on patients, as it encourages the consideration of treatment options early on in the condition. Participants preferred to rely on future Hba1c levels and their doctor's opinion to determine a change in treatment to insulin. Some participants had difficulty distinguishing between the different types of diabetes, including LADA. Others needed to ask questions about LADA in addition to written information. Conclusions. Participants were supportive of routine GADA testing, would prefer not to start insulin immediately following a diagnosis of LADA and needed to discuss treatment options with health professionals who were knowledgeable on LADA.

AB - Background. Latent autoimmune diabetes in adults (LADA) is a form of type 1 diabetes which in the UK is often diagnosed and treated as type 2 diabetes (T2D). People with LADA show slow progression to insulin dependence and can be distinguished from T2D by blood tests for glutamic acid decarboxylase autoantibodies (GADA). Aims. This study explores the views and experiences of patients who are newly diagnosed with LADA, with particular reference to (i) routine GADA testing; (ii) whether this diagnosis has any influence on the self-management of their diabetes; and (iii) the information needs of patients newly diagnosed with LADA. Methods. Ten consecutive patients newly diagnosed with LADA (GADA positive) were invited to participate in individual qualitative semi-structured interviews. Their views and experiences were analysed into codes and categories, using a constant comparative method. Findings. Participants supported routine GADA testing in all patients with diabetes because the provision of a correct diagnosis has an empowering effect on patients, as it encourages the consideration of treatment options early on in the condition. Participants preferred to rely on future Hba1c levels and their doctor's opinion to determine a change in treatment to insulin. Some participants had difficulty distinguishing between the different types of diabetes, including LADA. Others needed to ask questions about LADA in addition to written information. Conclusions. Participants were supportive of routine GADA testing, would prefer not to start insulin immediately following a diagnosis of LADA and needed to discuss treatment options with health professionals who were knowledgeable on LADA.

KW - Latent autoimmune diabetes in adults

KW - Patient views

KW - Qualitative

UR - http://www.scopus.com/inward/record.url?scp=47049105601&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=47049105601&partnerID=8YFLogxK

U2 - 10.1093/fampra/cmn016

DO - 10.1093/fampra/cmn016

M3 - Article

VL - 25

SP - 176

EP - 180

JO - Family Practice

JF - Family Practice

SN - 0263-2136

IS - 3

ER -