Relationship between genome and epigenome - challenges and requirements for future research

Geneviève Almouzni, Lucia Altucci, Bruno Amati, Neil Ashley, David Baulcombe, Nathalie Beaujean, Christoph Bock, Erik Bongcam-Rudloff, Jean Bousquet, Sigurd Braun, Brigitte Bressac de Paillerets, Marion Bussemakers, Laura Clarke, Ana Conesa, Xavier Estivill, Alireza Fazeli, Neža Grgurević, Ivo Gut, Bastiaan T. Heijmans, Sylvie HermouetJeanine Houwing-Duistermaat, Ilaria Iacobucci, Janez Ilaš, Raju Kandimalla, Susanne Krauss-Etschmann, Paul Lasko, Sören Lehmann, Anders Lindroth, Gregor Majdič, Eric Marcotte, Giovanni Martinelli, Nadine Martinet, Eric Meyer, Cristina Miceli, Ken Mills, Maria Moreno-Villanueva, Ghislaine Morvan, Dörthe Nickel, Beate Niesler, Mariusz Nowacki, Jacek Nowak, Stephan Ossowski, Mattia Pelizzola, Roland Pochet, Uroš Potočnik, Magdalena Radwanska, Jeroen Raes, Magnus Rattray, Mark D. Robinson, Bernard Roelen, Sascha Sauer, Dieter Schinzer, Eline Slagboom, Tim Spector, Hendrik G. Stunnenberg, Ekaterini Tiligada, Maria Elena Torres-Padilla, Roula Tsonaka, Ann V. Soom, Melita Vidaković, Martin Widschwendter

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.

Original languageEnglish
Article number487
JournalBMC genomics
Volume15
Issue number1
DOIs
Publication statusPublished - 18 Jun 2014

Keywords

  • Environment
  • Epigenome
  • Genome
  • Microbiome

ASJC Scopus subject areas

  • Biotechnology
  • Genetics

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  • Cite this

    Almouzni, G., Altucci, L., Amati, B., Ashley, N., Baulcombe, D., Beaujean, N., Bock, C., Bongcam-Rudloff, E., Bousquet, J., Braun, S., Paillerets, B. B. D., Bussemakers, M., Clarke, L., Conesa, A., Estivill, X., Fazeli, A., Grgurević, N., Gut, I., Heijmans, B. T., ... Widschwendter, M. (2014). Relationship between genome and epigenome - challenges and requirements for future research. BMC genomics, 15(1), [487]. https://doi.org/10.1186/1471-2164-15-487