Predicting temporal lobe epileptic seizures based on zero-crossing interval analysis in scalp EEG

Ali Shahidi Zandi, Reza Tafreshi, Manouchehr Javidan, Guy A. Dumont

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A novel real-time patient-specific algorithm to predict epileptic seizures is proposed. The method is based on the analysis of the positive zero-crossing intervals in the scalp electroencephalogram (EEG), describing the brain dynamics. In a moving-window analysis, the histogram of these intervals in each EEG epoch is computed, and the distribution of the histogram value in specific bins, selected using interictal and preictal references, is estimated based on the values obtained from the current epoch and the epochs of the last 5 min. The resulting distribution for each selected bin is then compared to two reference distributions (interictal and preictal), and a seizure prediction index is developed. Comparing this index with a patient-specific threshold for all EEG channels, a seizure prediction alarm is finally generated. The algorithm was tested on ∼15.5 hours of multichannel scalp EEG recordings from three patients with temporal lobe epilepsy, including 14 seizures. 86% of seizures were predicted with an average prediction time of 20.8 min and a false prediction rate of 0.12/hr.

Original languageEnglish
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Pages5537-5540
Number of pages4
DOIs
Publication statusPublished - 2010
Externally publishedYes
Event2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina
Duration: 31 Aug 20104 Sep 2010

Other

Other2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
CountryArgentina
CityBuenos Aires
Period31/8/104/9/10

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Electroencephalography
Bins
Brain

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Zandi, A. S., Tafreshi, R., Javidan, M., & Dumont, G. A. (2010). Predicting temporal lobe epileptic seizures based on zero-crossing interval analysis in scalp EEG. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 5537-5540). [5626764] https://doi.org/10.1109/IEMBS.2010.5626764

Predicting temporal lobe epileptic seizures based on zero-crossing interval analysis in scalp EEG. / Zandi, Ali Shahidi; Tafreshi, Reza; Javidan, Manouchehr; Dumont, Guy A.

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. 2010. p. 5537-5540 5626764.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zandi, AS, Tafreshi, R, Javidan, M & Dumont, GA 2010, Predicting temporal lobe epileptic seizures based on zero-crossing interval analysis in scalp EEG. in 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10., 5626764, pp. 5537-5540, 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10, Buenos Aires, Argentina, 31/8/10. https://doi.org/10.1109/IEMBS.2010.5626764
Zandi AS, Tafreshi R, Javidan M, Dumont GA. Predicting temporal lobe epileptic seizures based on zero-crossing interval analysis in scalp EEG. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. 2010. p. 5537-5540. 5626764 https://doi.org/10.1109/IEMBS.2010.5626764
Zandi, Ali Shahidi ; Tafreshi, Reza ; Javidan, Manouchehr ; Dumont, Guy A. / Predicting temporal lobe epileptic seizures based on zero-crossing interval analysis in scalp EEG. 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. 2010. pp. 5537-5540
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