Postgenomics: Proteomics and Bioinformatics in Cancer Research

Halima Bensmail, Abdelali Haoudi

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Now that the human genome is completed, the characterization of the proteins encoded by the sequence remains a challenging task. The study of the complete protein complement of the genome, the "proteome" referred to as proteomics, will be essential if new therapeutic drugs and new disease biomarkers for early diagnosis are to be developed. Research efforts are already underway to develop the technology necessary to compare the specific protein profiles of diseased versus nondiseased states. These technologies provide a wealth of information and rapidly generate large quantities of data. Processing the large amounts of data will lead to useful predictive mathematical descriptions of biological systems which will permit rapid identification of novel therapeutic targets and identification of metabolic disorders. Here, we present an overview of the current status and future research approaches in defining the cancer cell's proteome in combination with different bioinformatics and computational biology tools toward a better understanding of health and disease.

Original languageEnglish
Pages (from-to)217-230
Number of pages14
JournalJournal of Biomedicine and Biotechnology
Volume2003
Issue number4
DOIs
Publication statusPublished - 29 Oct 2003
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Genetics
  • Applied Microbiology and Biotechnology

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