Post-traumatic amnesia after closed head injury: A review of the literature and some suggestions for further research

S. Ahmed, R. Bierley, Javaid Sheikh, E. S. Date

Research output: Contribution to journalReview article

66 Citations (Scopus)


Post-traumatic amnesia (PTA) is a transient sequela of closed head injury (CHI). The term PTA has been in clinical use for over half a century, and generally refers to the subacute phase of recovery immediately after unconsciousness following CHI. The duration of PTA predicts functional outcome after CHI, but its pathophysiological mechanism is not known. This paper compares current methods of determining the duration of PTA, summarizes reports on neuropsychological deficits in PTA, reviews available data that allow inferences about its mechanism, and suggests methods for further exploration of its pathophysiology.

Original languageEnglish
Pages (from-to)765-780
Number of pages16
JournalBrain Injury
Issue number9
Publication statusPublished - 2000
Externally publishedYes


ASJC Scopus subject areas

  • Clinical Neurology

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