Polyarticular arthritis, independent of rheumatoid factor, is associated with poor functional outcome in recent onset inflammatory synovitis

L. Gerber, H. El-Gabalawy, Thurayya Arayssi, G. Furst, C. Yarboro, H. R. Schumacher

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The biological, physical and functional status change was measured in 104 patients with recent (< 1 year) onset synovitis. Measurements were taken initially and at 1 year. The purpose was to determine which biological and physical measures correlated with poor performance. Patients completed questionnaires quantifying activity, (the Human Activity Profile [HAP] and Sickness Impact Profile [SIP]), pain (Wisconsin Brief Pain Inventory), fatigue (Multidimensional Assessment of Fatigue), sleep, and mood (POMS and CESD). They were evaluated for articular involvement (Ritchie Index) and biological markers of disease activity (platelets, sedimentation rate, C-reactive protein and rheumatoid factor) (RF). In all, 30 men and 74 women participated. A total of 45 patients met the American College of Rheumatology criteria for rheumatoid arthritis (RA); of these, 24 were rheumatoid factor (RF) positive, 18 had spondylitis, and 41 had unclassified arthritis. Low activity level at 1 year (HAP and SIP) correlated with high numbers of inflamed joints initially (p < 0.002); with more than 10 involved joints regardless of diagnostic group (p = 0.001); and joint symmetry (p < 0.009) A high platelet count was associated with low activity level at 1 year (p = 0.01); and high sedimentation rate was associated with more pain (p < 0.05). Low activity level (p < 0.04), fatigue (p = 0.03) and sleeplessness (p = 0.02) were correlated with RF + RA.

Original languageEnglish
Pages (from-to)105-109
Number of pages5
JournalJournal of Back and Musculoskeletal Rehabilitation
Volume14
Issue number3
Publication statusPublished - 2000
Externally publishedYes

Fingerprint

Synovitis
Rheumatoid Factor
Arthritis
Joints
Sickness Impact Profile
Fatigue
Human Activities
Pain
Rheumatoid Arthritis
Spondylitis
Sleep Initiation and Maintenance Disorders
Platelet Count
C-Reactive Protein
Sleep
Blood Platelets
Biomarkers
Equipment and Supplies

Keywords

  • Functional activity
  • Inflammatory arthritis

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

Cite this

Polyarticular arthritis, independent of rheumatoid factor, is associated with poor functional outcome in recent onset inflammatory synovitis. / Gerber, L.; El-Gabalawy, H.; Arayssi, Thurayya; Furst, G.; Yarboro, C.; Schumacher, H. R.

In: Journal of Back and Musculoskeletal Rehabilitation, Vol. 14, No. 3, 2000, p. 105-109.

Research output: Contribution to journalArticle

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