Pituitary apoplexy after subtotal thyroidectomy in an acromegalic patient with a large goiter

Kazunobu Kato, Masakazu Nobori, Yoshihiro Miyauchi, Motoki Ohnisi, Shyoji Yoshida, Shigeru Oya, Shin Tomita, Tomoshige Kino

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8 Citations (Scopus)


A case of pituitary apoplexy occurring after subtotal thyroidectomy in an acromegalic woman with a large adenomatous goiter is described. The patient had severe apnea because the large goiter was causing airway compression. Prior to the planned hypophysectomy, a subtotal thyroidectomy was performed to relieve tracheal stenosis. Shortly after the operation, the patient developed a headache that lasted for several days. The serum levels of growth hormone and somatomedin-C spontaneously normalized seventeen days after this episode and have remained normal for two years. Pituitary apoplexy was thought to have caused the observed results without deterioration of the pituitary function.

Original languageEnglish
Pages (from-to)472-477
Number of pages6
JournalInternal Medicine
Issue number6
Publication statusPublished - Jun 1996



  • Acromegaly
  • Airway obstruction
  • Diabetes mellitus
  • Thyroid goiter

ASJC Scopus subject areas

  • Internal Medicine

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