PET scan before CABG in diabetes

Hesham Hegazy, Ayman Refaei, Azza Assedique, Shukri Alsaif, Mayada Taha, Mostafa Refaei, Naser Elkum, Hamed Alomran, Zohair Al-Halees

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Abstract

Background and objectives: Since the role of positron emission tomography (PET) scanning in diabetes is not clear, this study sought to assess the usefulness of PET scanning for viability in this patient group. Methods: Forty-four per cent insulin-treated, and 56% non-insulin-treated diabetic patients with severely impaired left ventricular function (LVEF 29±9%) underwent first coronary artery bypass grafting (CABG). Pre-operative viability was assessed by PET scan. Results: Eighty-two per cent of patients received ≥ 3 grafts. Twenty-seven patients were discharged home and followed for a mean 3.5±1.6 years. Postoperative LVEF improved to 40±9 (p<0.0001). Multiple regression analysis indicated that the only variable that predicted improvement in global LV function was presence of hibernating segments at PET scan. The single variable that predicted deterioration of LVEF was the number of segments with reduced perfusion and metabolism at PET scan. Conclusion: PET scan is an accurate tool for prediction of global left ventricular function recovery following CABG in people with diabetes.

Original languageEnglish
Pages (from-to)32-37
Number of pages6
JournalBritish Journal of Diabetes and Vascular Disease
Volume7
Issue number1
DOIs
Publication statusPublished - Jan 2007
Externally publishedYes

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Keywords

  • Bypass surgery
  • Coronary artery disease
  • Diabetes
  • Hibernating myocardium
  • Impaired left ventricular function

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Hegazy, H., Refaei, A., Assedique, A., Alsaif, S., Taha, M., Refaei, M., Elkum, N., Alomran, H., & Al-Halees, Z. (2007). PET scan before CABG in diabetes. British Journal of Diabetes and Vascular Disease, 7(1), 32-37. https://doi.org/10.1177/14746514070070010601