Nucleobase peptide amphiphiles

Christopher J. Serpell, Maciej Barłóg, Kaustuv Basu, Johans F. Fakhoury, Hassan S. Bazzi, Hanadi F. Sleiman

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A new class of peptide materials is introduced, integrating orthogonal aspects of peptide, nucleoside, and amphiphile chemistry. In solution, species such as rod-like or helical micelles are formed, which can lead to nanoribbons under lateral or longitudinal hierarchical growth regimes. Gelation of a wide range of solvents can be induced, including water and aqueous buffer, providing new avenues for nucleobase-specific electrophoresis, oligonucleotide delivery and bioactive cell growth media.

Original languageEnglish
Pages (from-to)348-354
Number of pages7
JournalMaterials Horizons
Volume1
Issue number3
DOIs
Publication statusPublished - 1 May 2014

Fingerprint

Amphiphiles
Peptides
Nanoribbons
Carbon Nanotubes
Oligonucleotides
Cell growth
Micelles
Gelation
Electrophoresis
Nucleosides
Buffers
Water

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Process Chemistry and Technology
  • Electrical and Electronic Engineering

Cite this

Serpell, C. J., Barłóg, M., Basu, K., Fakhoury, J. F., Bazzi, H. S., & Sleiman, H. F. (2014). Nucleobase peptide amphiphiles. Materials Horizons, 1(3), 348-354. https://doi.org/10.1039/c3mh00154g

Nucleobase peptide amphiphiles. / Serpell, Christopher J.; Barłóg, Maciej; Basu, Kaustuv; Fakhoury, Johans F.; Bazzi, Hassan S.; Sleiman, Hanadi F.

In: Materials Horizons, Vol. 1, No. 3, 01.05.2014, p. 348-354.

Research output: Contribution to journalArticle

Serpell, CJ, Barłóg, M, Basu, K, Fakhoury, JF, Bazzi, HS & Sleiman, HF 2014, 'Nucleobase peptide amphiphiles', Materials Horizons, vol. 1, no. 3, pp. 348-354. https://doi.org/10.1039/c3mh00154g
Serpell CJ, Barłóg M, Basu K, Fakhoury JF, Bazzi HS, Sleiman HF. Nucleobase peptide amphiphiles. Materials Horizons. 2014 May 1;1(3):348-354. https://doi.org/10.1039/c3mh00154g
Serpell, Christopher J. ; Barłóg, Maciej ; Basu, Kaustuv ; Fakhoury, Johans F. ; Bazzi, Hassan S. ; Sleiman, Hanadi F. / Nucleobase peptide amphiphiles. In: Materials Horizons. 2014 ; Vol. 1, No. 3. pp. 348-354.
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