Nucleobase peptide amphiphiles

Christopher J. Serpell, Maciej Barłóg, Kaustuv Basu, Johans F. Fakhoury, Hassan S. Bazzi, Hanadi F. Sleiman

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12 Citations (Scopus)

Abstract

A new class of peptide materials is introduced, integrating orthogonal aspects of peptide, nucleoside, and amphiphile chemistry. In solution, species such as rod-like or helical micelles are formed, which can lead to nanoribbons under lateral or longitudinal hierarchical growth regimes. Gelation of a wide range of solvents can be induced, including water and aqueous buffer, providing new avenues for nucleobase-specific electrophoresis, oligonucleotide delivery and bioactive cell growth media.

Original languageEnglish
Pages (from-to)348-354
Number of pages7
JournalMaterials Horizons
Volume1
Issue number3
DOIs
Publication statusPublished - 1 May 2014

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ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Process Chemistry and Technology
  • Electrical and Electronic Engineering

Cite this

Serpell, C. J., Barłóg, M., Basu, K., Fakhoury, J. F., Bazzi, H. S., & Sleiman, H. F. (2014). Nucleobase peptide amphiphiles. Materials Horizons, 1(3), 348-354. https://doi.org/10.1039/c3mh00154g