New insights into the pathogenesis and therapy of Behçet's disease

Thurayya Arayssi, Ayad Hamdan

Research output: Contribution to journalReview article

45 Citations (Scopus)

Abstract

Behçet's disease is a chronic multisystem inflammatory disease characterized by the predominance of Th1 cytokines. The human leukocyte antigen-B 51 gene is associated with the disease in several ethnic groups, but it is not certain whether it is the susceptibility gene or if it is in linkage disequilibrium with other genes. Recent studies of polymorphisms of neighboring, as well as distant, genes to human leukocyte antigen-B 51 are helpful in elucidating the pathogenesis of the disease and could have therapeutic implications.

Original languageEnglish
Pages (from-to)183-188
Number of pages6
JournalCurrent Opinion in Pharmacology
Volume4
Issue number2
DOIs
Publication statusPublished - Apr 2004
Externally publishedYes

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HLA Antigens
Genes
Linkage Disequilibrium
Therapeutics
Ethnic Groups
Cytokines

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Pharmacology

Cite this

New insights into the pathogenesis and therapy of Behçet's disease. / Arayssi, Thurayya; Hamdan, Ayad.

In: Current Opinion in Pharmacology, Vol. 4, No. 2, 04.2004, p. 183-188.

Research output: Contribution to journalReview article

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