Neuropathy of type 1 diabetes in the Arab world: A systematic review and meta-analysis

Ussama M. Abdel-Motal, Essam Mohamed, Haissam Abou-Saleh, Hatem Zayed

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aims Although type 1 diabetes (T1D) is a common disease in the Arab nations, there is no data available on the prevalence of peripheral neuropathy (PN) among T1D subjects in Arab countries. The aim of this study is to analyze the prevalence of PN in T1D subjects via published literature and to draw attention to the dearth of the published work in this serious complication of T1D. Methods A meta-analysis was performed on studies representing different Arab countries with a total number of 2243 T1D subjects. Results The pooled prevalence of PN among T1D subjects in the Arab region was estimated as 18% with 95% confidence intervals (CI): 0.09–0.34. The PN prevalence was significantly higher in the >16-yr age group, with 59.1% (95% CI: 0.45–0.72) compared to 9.5% (95% CI: 0.05–0.19) in the <16-yr age group. Furthermore, the PN prevalence was significantly higher in the group with more than 10-yr T1D, 35% (95% CI: 0.15–0.62) than in the group with less than 10-yr T1D, 9.4% (95% CI: 0.04–0.21). Conclusion In Arab countries, PN is common in adults and children with T1D, but prevalence varies widely. Older age Arab people (>16 years) with T1D are affected more with PN than younger age Arab people (<16 years). PN is more frequently present in Arab subjects with a longer duration of T1D diabetes than in those with shorter duration.

Original languageEnglish
Pages (from-to)172-180
Number of pages9
JournalDiabetes Research and Clinical Practice
Volume127
DOIs
Publication statusPublished - 1 May 2017

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Arab World
Type 1 Diabetes Mellitus
Meta-Analysis
Peripheral Nervous System Diseases
Middle East
Confidence Intervals
Age Groups

Keywords

  • Arab nations
  • Meta-analysis
  • Neuropathy
  • Peripheral
  • Prevalence
  • Type 1 diabetes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Neuropathy of type 1 diabetes in the Arab world : A systematic review and meta-analysis. / Abdel-Motal, Ussama M.; Mohamed, Essam; Abou-Saleh, Haissam; Zayed, Hatem.

In: Diabetes Research and Clinical Practice, Vol. 127, 01.05.2017, p. 172-180.

Research output: Contribution to journalArticle

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title = "Neuropathy of type 1 diabetes in the Arab world: A systematic review and meta-analysis",
abstract = "Aims Although type 1 diabetes (T1D) is a common disease in the Arab nations, there is no data available on the prevalence of peripheral neuropathy (PN) among T1D subjects in Arab countries. The aim of this study is to analyze the prevalence of PN in T1D subjects via published literature and to draw attention to the dearth of the published work in this serious complication of T1D. Methods A meta-analysis was performed on studies representing different Arab countries with a total number of 2243 T1D subjects. Results The pooled prevalence of PN among T1D subjects in the Arab region was estimated as 18{\%} with 95{\%} confidence intervals (CI): 0.09–0.34. The PN prevalence was significantly higher in the >16-yr age group, with 59.1{\%} (95{\%} CI: 0.45–0.72) compared to 9.5{\%} (95{\%} CI: 0.05–0.19) in the <16-yr age group. Furthermore, the PN prevalence was significantly higher in the group with more than 10-yr T1D, 35{\%} (95{\%} CI: 0.15–0.62) than in the group with less than 10-yr T1D, 9.4{\%} (95{\%} CI: 0.04–0.21). Conclusion In Arab countries, PN is common in adults and children with T1D, but prevalence varies widely. Older age Arab people (>16 years) with T1D are affected more with PN than younger age Arab people (<16 years). PN is more frequently present in Arab subjects with a longer duration of T1D diabetes than in those with shorter duration.",
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T1 - Neuropathy of type 1 diabetes in the Arab world

T2 - A systematic review and meta-analysis

AU - Abdel-Motal, Ussama M.

AU - Mohamed, Essam

AU - Abou-Saleh, Haissam

AU - Zayed, Hatem

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Aims Although type 1 diabetes (T1D) is a common disease in the Arab nations, there is no data available on the prevalence of peripheral neuropathy (PN) among T1D subjects in Arab countries. The aim of this study is to analyze the prevalence of PN in T1D subjects via published literature and to draw attention to the dearth of the published work in this serious complication of T1D. Methods A meta-analysis was performed on studies representing different Arab countries with a total number of 2243 T1D subjects. Results The pooled prevalence of PN among T1D subjects in the Arab region was estimated as 18% with 95% confidence intervals (CI): 0.09–0.34. The PN prevalence was significantly higher in the >16-yr age group, with 59.1% (95% CI: 0.45–0.72) compared to 9.5% (95% CI: 0.05–0.19) in the <16-yr age group. Furthermore, the PN prevalence was significantly higher in the group with more than 10-yr T1D, 35% (95% CI: 0.15–0.62) than in the group with less than 10-yr T1D, 9.4% (95% CI: 0.04–0.21). Conclusion In Arab countries, PN is common in adults and children with T1D, but prevalence varies widely. Older age Arab people (>16 years) with T1D are affected more with PN than younger age Arab people (<16 years). PN is more frequently present in Arab subjects with a longer duration of T1D diabetes than in those with shorter duration.

AB - Aims Although type 1 diabetes (T1D) is a common disease in the Arab nations, there is no data available on the prevalence of peripheral neuropathy (PN) among T1D subjects in Arab countries. The aim of this study is to analyze the prevalence of PN in T1D subjects via published literature and to draw attention to the dearth of the published work in this serious complication of T1D. Methods A meta-analysis was performed on studies representing different Arab countries with a total number of 2243 T1D subjects. Results The pooled prevalence of PN among T1D subjects in the Arab region was estimated as 18% with 95% confidence intervals (CI): 0.09–0.34. The PN prevalence was significantly higher in the >16-yr age group, with 59.1% (95% CI: 0.45–0.72) compared to 9.5% (95% CI: 0.05–0.19) in the <16-yr age group. Furthermore, the PN prevalence was significantly higher in the group with more than 10-yr T1D, 35% (95% CI: 0.15–0.62) than in the group with less than 10-yr T1D, 9.4% (95% CI: 0.04–0.21). Conclusion In Arab countries, PN is common in adults and children with T1D, but prevalence varies widely. Older age Arab people (>16 years) with T1D are affected more with PN than younger age Arab people (<16 years). PN is more frequently present in Arab subjects with a longer duration of T1D diabetes than in those with shorter duration.

KW - Arab nations

KW - Meta-analysis

KW - Neuropathy

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KW - Prevalence

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