Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene

Young Hyun No, Nam Hyeong Kim, Bramaramba Gnapareddy, Bumjoon Choi, Yong Tae Kim, Sreekantha Reddy Dugasani, One-Sun Lee, Kook Han Kim, Young Seon Ko, Seungwoo Lee, Sang Woo Lee, Sung Ha Park, Kilho Eom, Yong Ho Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)


Peptide assemblies have received significant attention because of their important role in biology and applications in bionanotechnology. Despite recent efforts to elucidate the principles of peptide self-assembly for developing novel functional devices, peptide self-assembly on two-dimensional nanomaterials has remained challenging. Here, we report nature-inspired two-dimensional peptide self-assembly on pristine graphene via optimization of peptide-peptide and peptide-graphene interactions. Two-dimensional peptide self-assembly was designed based on statistical analyses of >104 protein structures existing in nature and atomistic simulation-based structure predictions. We characterized the structures and surface properties of the self-assembled peptide formed on pristine graphene. Our study provides insights into the formation of peptide assemblies coupled with two-dimensional nanomaterials for further development of nanobiocomposite devices.

Original languageEnglish
Pages (from-to)3734-3739
Number of pages6
JournalJournal of Physical Chemistry Letters
Issue number16
Publication statusPublished - 17 Aug 2017


ASJC Scopus subject areas

  • Materials Science(all)

Cite this

No, Y. H., Kim, N. H., Gnapareddy, B., Choi, B., Kim, Y. T., Dugasani, S. R., Lee, O-S., Kim, K. H., Ko, Y. S., Lee, S., Lee, S. W., Park, S. H., Eom, K., & Kim, Y. H. (2017). Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene. Journal of Physical Chemistry Letters, 8(16), 3734-3739.