Nanoelectrode arrays for measuring Sympathetic Nervous Activity

Aamer Mahmoud, Peng Sheng Chen, A. George Akingba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper reports on the use of arrays of nanoelectrodes to measure activity of the Sympathetic Nervous System. Measurements of the Sympathetic Nervous Activity (SNA) have not been easy; primarily because of poor signal-to-noise ratio (SNR). We report improved SNR of SNA measurements achieved by the use of novel Planar Nanoelectrode Arrays (PNA). Nano scale features on the electrodes provide increased contact area with the host nerve reducing the limiting (Johnson) noise. These electrodes are fabricated using standard CMOS compatible fabrication techniques on a high resistivity silicon substrate and used to measure SNA in test animals. For comparison, traditional wire electrodes were used simultaneously to measure the same signal. The PNAs consistently exhibit significant improvement in the SNR of the measured SNA (35.71 dB vs. 25.08 dB for the wire electrode). Moreover, the PNAs are capable of recording events lost in the noise floor of the wire electrodes.

Original languageEnglish
Title of host publicationProceedings of IEEE Sensors
Pages1241-1244
Number of pages4
DOIs
Publication statusPublished - 2011
Externally publishedYes
Event10th IEEE SENSORS Conference 2011, SENSORS 2011 - Limerick, Ireland
Duration: 28 Oct 201131 Oct 2011

Other

Other10th IEEE SENSORS Conference 2011, SENSORS 2011
CountryIreland
CityLimerick
Period28/10/1131/10/11

Fingerprint

Electrodes
Signal to noise ratio
Wire
Neurology
Animals
Fabrication
Silicon
Substrates

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Cite this

Mahmoud, A., Chen, P. S., & George Akingba, A. (2011). Nanoelectrode arrays for measuring Sympathetic Nervous Activity. In Proceedings of IEEE Sensors (pp. 1241-1244). [6127022] https://doi.org/10.1109/ICSENS.2011.6127022

Nanoelectrode arrays for measuring Sympathetic Nervous Activity. / Mahmoud, Aamer; Chen, Peng Sheng; George Akingba, A.

Proceedings of IEEE Sensors. 2011. p. 1241-1244 6127022.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mahmoud, A, Chen, PS & George Akingba, A 2011, Nanoelectrode arrays for measuring Sympathetic Nervous Activity. in Proceedings of IEEE Sensors., 6127022, pp. 1241-1244, 10th IEEE SENSORS Conference 2011, SENSORS 2011, Limerick, Ireland, 28/10/11. https://doi.org/10.1109/ICSENS.2011.6127022
Mahmoud A, Chen PS, George Akingba A. Nanoelectrode arrays for measuring Sympathetic Nervous Activity. In Proceedings of IEEE Sensors. 2011. p. 1241-1244. 6127022 https://doi.org/10.1109/ICSENS.2011.6127022
Mahmoud, Aamer ; Chen, Peng Sheng ; George Akingba, A. / Nanoelectrode arrays for measuring Sympathetic Nervous Activity. Proceedings of IEEE Sensors. 2011. pp. 1241-1244
@inproceedings{9d2e3b7781b44d788d7e702d54951fdc,
title = "Nanoelectrode arrays for measuring Sympathetic Nervous Activity",
abstract = "This paper reports on the use of arrays of nanoelectrodes to measure activity of the Sympathetic Nervous System. Measurements of the Sympathetic Nervous Activity (SNA) have not been easy; primarily because of poor signal-to-noise ratio (SNR). We report improved SNR of SNA measurements achieved by the use of novel Planar Nanoelectrode Arrays (PNA). Nano scale features on the electrodes provide increased contact area with the host nerve reducing the limiting (Johnson) noise. These electrodes are fabricated using standard CMOS compatible fabrication techniques on a high resistivity silicon substrate and used to measure SNA in test animals. For comparison, traditional wire electrodes were used simultaneously to measure the same signal. The PNAs consistently exhibit significant improvement in the SNR of the measured SNA (35.71 dB vs. 25.08 dB for the wire electrode). Moreover, the PNAs are capable of recording events lost in the noise floor of the wire electrodes.",
author = "Aamer Mahmoud and Chen, {Peng Sheng} and {George Akingba}, A.",
year = "2011",
doi = "10.1109/ICSENS.2011.6127022",
language = "English",
isbn = "9781424492886",
pages = "1241--1244",
booktitle = "Proceedings of IEEE Sensors",

}

TY - GEN

T1 - Nanoelectrode arrays for measuring Sympathetic Nervous Activity

AU - Mahmoud, Aamer

AU - Chen, Peng Sheng

AU - George Akingba, A.

PY - 2011

Y1 - 2011

N2 - This paper reports on the use of arrays of nanoelectrodes to measure activity of the Sympathetic Nervous System. Measurements of the Sympathetic Nervous Activity (SNA) have not been easy; primarily because of poor signal-to-noise ratio (SNR). We report improved SNR of SNA measurements achieved by the use of novel Planar Nanoelectrode Arrays (PNA). Nano scale features on the electrodes provide increased contact area with the host nerve reducing the limiting (Johnson) noise. These electrodes are fabricated using standard CMOS compatible fabrication techniques on a high resistivity silicon substrate and used to measure SNA in test animals. For comparison, traditional wire electrodes were used simultaneously to measure the same signal. The PNAs consistently exhibit significant improvement in the SNR of the measured SNA (35.71 dB vs. 25.08 dB for the wire electrode). Moreover, the PNAs are capable of recording events lost in the noise floor of the wire electrodes.

AB - This paper reports on the use of arrays of nanoelectrodes to measure activity of the Sympathetic Nervous System. Measurements of the Sympathetic Nervous Activity (SNA) have not been easy; primarily because of poor signal-to-noise ratio (SNR). We report improved SNR of SNA measurements achieved by the use of novel Planar Nanoelectrode Arrays (PNA). Nano scale features on the electrodes provide increased contact area with the host nerve reducing the limiting (Johnson) noise. These electrodes are fabricated using standard CMOS compatible fabrication techniques on a high resistivity silicon substrate and used to measure SNA in test animals. For comparison, traditional wire electrodes were used simultaneously to measure the same signal. The PNAs consistently exhibit significant improvement in the SNR of the measured SNA (35.71 dB vs. 25.08 dB for the wire electrode). Moreover, the PNAs are capable of recording events lost in the noise floor of the wire electrodes.

UR - http://www.scopus.com/inward/record.url?scp=84863399616&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863399616&partnerID=8YFLogxK

U2 - 10.1109/ICSENS.2011.6127022

DO - 10.1109/ICSENS.2011.6127022

M3 - Conference contribution

SN - 9781424492886

SP - 1241

EP - 1244

BT - Proceedings of IEEE Sensors

ER -