Using higher frequency bands becomes an essential demand resulting from the explosive wireless traffic needs and the spectrum shortage of the currently used bands. This paper presents an overview on the terahertz technology and its application in the area of multi-input multi-output antenna system and in-vivo nano-communication. In addition, it presents a preliminary study on applying multiple input-single output (MISO) antenna technique to investigate the signal propagation and antenna diversity techniques inside the human skin tissues, which is represented by three layers: stratum corneum (SC), epidermis, and dermis layers, in the terahertz (THz) frequency range (0.8-1.2) THz. The spatial antenna diversity is investigated in this study to understand MISO system performance for two different in-vivo channels resulting from the signal propagation between two transmitting antennas, located at the dermis layer, and one receiving antenna, located at epidermis layer. Three techniques are investigated: selection combining (SC), equal-gain combing (EGC), and maximum-ratio combining (MRC). The initial study indicates that using multiple antenna technique with THz might be not useful for in-vivo nano-communication.