Molecular magnetic resonance imaging in cancer

Mohammad Haris, Santosh K. Yadav, Arshi Rizwan, Anup Singh, Ena Wang, Hari Hariharan, Ravinder Reddy, Francesco M. Marincola

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

The ability to identify key biomolecules and molecular changes associated with cancer malignancy and the capacity to monitor the therapeutic outcome against these targets is critically important for cancer treatment. Recent developments in molecular imaging based on magnetic resonance (MR) techniques have provided researchers and clinicians with new tools to improve most facets of cancer care. Molecular imaging is broadly described as imaging techniques used to detect molecular signature at the cellular and gene expression levels. This article reviews both established and emerging molecular MR techniques in oncology and discusses the potential of these techniques in improving the clinical cancer care. It also discusses how molecular MR, in conjunction with other structural and functional MR imaging techniques, paves the way for developing tailored treatment strategies to enhance cancer care.

Original languageEnglish
Article number313
JournalJournal of Translational Medicine
Volume13
Issue number1
DOIs
Publication statusPublished - 23 Sep 2015

Fingerprint

Magnetic resonance
Molecular imaging
Oncology
Magnetic Resonance Imaging
Imaging techniques
Neoplasms
Molecular Imaging
Magnetic Resonance Spectroscopy
Biomolecules
Gene expression
Research Personnel
Gene Expression

Keywords

  • Cancer
  • Cancer immunotherapy
  • Chemical exchange saturation transfer (CEST) imaging
  • Hyperpolarization
  • Magnetic resonance imaging
  • Magnetic resonance spectroscopy
  • Reporter genes

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Molecular magnetic resonance imaging in cancer. / Haris, Mohammad; Yadav, Santosh K.; Rizwan, Arshi; Singh, Anup; Wang, Ena; Hariharan, Hari; Reddy, Ravinder; Marincola, Francesco M.

In: Journal of Translational Medicine, Vol. 13, No. 1, 313, 23.09.2015.

Research output: Contribution to journalReview article

Haris, Mohammad ; Yadav, Santosh K. ; Rizwan, Arshi ; Singh, Anup ; Wang, Ena ; Hariharan, Hari ; Reddy, Ravinder ; Marincola, Francesco M. / Molecular magnetic resonance imaging in cancer. In: Journal of Translational Medicine. 2015 ; Vol. 13, No. 1.
@article{d261d9e2e193484a89152208a5fdd2a6,
title = "Molecular magnetic resonance imaging in cancer",
abstract = "The ability to identify key biomolecules and molecular changes associated with cancer malignancy and the capacity to monitor the therapeutic outcome against these targets is critically important for cancer treatment. Recent developments in molecular imaging based on magnetic resonance (MR) techniques have provided researchers and clinicians with new tools to improve most facets of cancer care. Molecular imaging is broadly described as imaging techniques used to detect molecular signature at the cellular and gene expression levels. This article reviews both established and emerging molecular MR techniques in oncology and discusses the potential of these techniques in improving the clinical cancer care. It also discusses how molecular MR, in conjunction with other structural and functional MR imaging techniques, paves the way for developing tailored treatment strategies to enhance cancer care.",
keywords = "Cancer, Cancer immunotherapy, Chemical exchange saturation transfer (CEST) imaging, Hyperpolarization, Magnetic resonance imaging, Magnetic resonance spectroscopy, Reporter genes",
author = "Mohammad Haris and Yadav, {Santosh K.} and Arshi Rizwan and Anup Singh and Ena Wang and Hari Hariharan and Ravinder Reddy and Marincola, {Francesco M.}",
year = "2015",
month = "9",
day = "23",
doi = "10.1186/s12967-015-0659-x",
language = "English",
volume = "13",
journal = "Journal of Translational Medicine",
issn = "1479-5876",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Molecular magnetic resonance imaging in cancer

AU - Haris, Mohammad

AU - Yadav, Santosh K.

AU - Rizwan, Arshi

AU - Singh, Anup

AU - Wang, Ena

AU - Hariharan, Hari

AU - Reddy, Ravinder

AU - Marincola, Francesco M.

PY - 2015/9/23

Y1 - 2015/9/23

N2 - The ability to identify key biomolecules and molecular changes associated with cancer malignancy and the capacity to monitor the therapeutic outcome against these targets is critically important for cancer treatment. Recent developments in molecular imaging based on magnetic resonance (MR) techniques have provided researchers and clinicians with new tools to improve most facets of cancer care. Molecular imaging is broadly described as imaging techniques used to detect molecular signature at the cellular and gene expression levels. This article reviews both established and emerging molecular MR techniques in oncology and discusses the potential of these techniques in improving the clinical cancer care. It also discusses how molecular MR, in conjunction with other structural and functional MR imaging techniques, paves the way for developing tailored treatment strategies to enhance cancer care.

AB - The ability to identify key biomolecules and molecular changes associated with cancer malignancy and the capacity to monitor the therapeutic outcome against these targets is critically important for cancer treatment. Recent developments in molecular imaging based on magnetic resonance (MR) techniques have provided researchers and clinicians with new tools to improve most facets of cancer care. Molecular imaging is broadly described as imaging techniques used to detect molecular signature at the cellular and gene expression levels. This article reviews both established and emerging molecular MR techniques in oncology and discusses the potential of these techniques in improving the clinical cancer care. It also discusses how molecular MR, in conjunction with other structural and functional MR imaging techniques, paves the way for developing tailored treatment strategies to enhance cancer care.

KW - Cancer

KW - Cancer immunotherapy

KW - Chemical exchange saturation transfer (CEST) imaging

KW - Hyperpolarization

KW - Magnetic resonance imaging

KW - Magnetic resonance spectroscopy

KW - Reporter genes

UR - http://www.scopus.com/inward/record.url?scp=84942243069&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942243069&partnerID=8YFLogxK

U2 - 10.1186/s12967-015-0659-x

DO - 10.1186/s12967-015-0659-x

M3 - Review article

VL - 13

JO - Journal of Translational Medicine

JF - Journal of Translational Medicine

SN - 1479-5876

IS - 1

M1 - 313

ER -