Maternal immunisation

collaborating with mother nature

Arnaud Marchant, Manish Sadarangani, Mathieu Garand, Nicolas Dauby, Valerie Verhasselt, Lenore Pereira, Gordean Bjornson, Christine E. Jones, Scott A. Halperin, Kathryn M. Edwards, Paul Heath, Peter J. Openshaw, David W. Scheifele, Tobias R. Kollmann

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

Maternal immunisation has the potential to substantially reduce morbidity and mortality from infectious diseases after birth. The success of tetanus, influenza, and pertussis immunisation during pregnancy has led to consideration of additional maternal immunisation strategies to prevent group B streptococcus and respiratory syncytial virus infections, among others. However, many gaps in knowledge regarding the immunobiology of maternal immunisation prevent the optimal design and application of this successful public health intervention. Therefore, we did an innovative landscape analysis to identify research priorities. Key topics were delineated through review of the published literature, consultation with vaccine developers and regulatory agencies, and a collaborative workshop that gathered experts across several maternal immunisation initiatives—group B streptococcus, respiratory syncytial virus, pertussis, and influenza. Finally, a global online survey prioritised the identified knowledge gaps on the basis of expert opinion about their importance and relevance. Here we present the results of this worldwide landscape analysis and discuss the identified research gaps.

Original languageEnglish
Pages (from-to)e197-e208
JournalThe Lancet Infectious Diseases
Volume17
Issue number7
DOIs
Publication statusPublished - 1 Jul 2017
Externally publishedYes

Fingerprint

Immunization
Mothers
Whooping Cough
Human Influenza
Respiratory Syncytial Virus Infections
Streptococcus agalactiae
Respiratory Syncytial Viruses
Tetanus
Expert Testimony
Streptococcus
Research
Communicable Diseases
Referral and Consultation
Vaccines
Public Health
Parturition
Morbidity
Education
Pregnancy
Mortality

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Marchant, A., Sadarangani, M., Garand, M., Dauby, N., Verhasselt, V., Pereira, L., ... Kollmann, T. R. (2017). Maternal immunisation: collaborating with mother nature. The Lancet Infectious Diseases, 17(7), e197-e208. https://doi.org/10.1016/S1473-3099(17)30229-3

Maternal immunisation : collaborating with mother nature. / Marchant, Arnaud; Sadarangani, Manish; Garand, Mathieu; Dauby, Nicolas; Verhasselt, Valerie; Pereira, Lenore; Bjornson, Gordean; Jones, Christine E.; Halperin, Scott A.; Edwards, Kathryn M.; Heath, Paul; Openshaw, Peter J.; Scheifele, David W.; Kollmann, Tobias R.

In: The Lancet Infectious Diseases, Vol. 17, No. 7, 01.07.2017, p. e197-e208.

Research output: Contribution to journalReview article

Marchant, A, Sadarangani, M, Garand, M, Dauby, N, Verhasselt, V, Pereira, L, Bjornson, G, Jones, CE, Halperin, SA, Edwards, KM, Heath, P, Openshaw, PJ, Scheifele, DW & Kollmann, TR 2017, 'Maternal immunisation: collaborating with mother nature', The Lancet Infectious Diseases, vol. 17, no. 7, pp. e197-e208. https://doi.org/10.1016/S1473-3099(17)30229-3
Marchant A, Sadarangani M, Garand M, Dauby N, Verhasselt V, Pereira L et al. Maternal immunisation: collaborating with mother nature. The Lancet Infectious Diseases. 2017 Jul 1;17(7):e197-e208. https://doi.org/10.1016/S1473-3099(17)30229-3
Marchant, Arnaud ; Sadarangani, Manish ; Garand, Mathieu ; Dauby, Nicolas ; Verhasselt, Valerie ; Pereira, Lenore ; Bjornson, Gordean ; Jones, Christine E. ; Halperin, Scott A. ; Edwards, Kathryn M. ; Heath, Paul ; Openshaw, Peter J. ; Scheifele, David W. ; Kollmann, Tobias R. / Maternal immunisation : collaborating with mother nature. In: The Lancet Infectious Diseases. 2017 ; Vol. 17, No. 7. pp. e197-e208.
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