Masstrix reloaded: Combined analysis and visualization of tran-scriptome and metabolome data

Brigitte Wägele, Michael Witting, Philippe Schmitt-Kopplin, Karsten Suhre

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Systems Biology is a field in biological science that focuses on the combination of several or all "omics"-approaches in order to find out how genes, transcripts, proteins and metabolites act together in the network of life. Metabolomics as analog to genomics, transcriptomics and proteomics is more and more integrated into biological studies and often transcriptomic and metabolomic experiments are combined in one setup. At a first glance both data types seem to be completely different, but both produce information on biological entities, either transcripts or metabolites. Both types can be overlaid on metabolic pathways to obtain biological information on the studied system. For the joint analysis of both data types the MassTRIX webserver was updated. MassTRIX is freely available at www.masstrix.org.

Original languageEnglish
Article numbere39860
JournalPLoS One
Volume7
Issue number7
DOIs
Publication statusPublished - 6 Jul 2012
Externally publishedYes

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metabolome
Metabolomics
Metabolome
metabolomics
Metabolites
transcriptomics
Visualization
metabolites
Biological Sciences
Systems Biology
Biological Science Disciplines
Genomics
Metabolic Networks and Pathways
Proteomics
proteomics
biochemical pathways
data analysis
Genes
genomics
Proteins

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Masstrix reloaded : Combined analysis and visualization of tran-scriptome and metabolome data. / Wägele, Brigitte; Witting, Michael; Schmitt-Kopplin, Philippe; Suhre, Karsten.

In: PLoS One, Vol. 7, No. 7, e39860, 06.07.2012.

Research output: Contribution to journalArticle

Wägele, Brigitte ; Witting, Michael ; Schmitt-Kopplin, Philippe ; Suhre, Karsten. / Masstrix reloaded : Combined analysis and visualization of tran-scriptome and metabolome data. In: PLoS One. 2012 ; Vol. 7, No. 7.
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