Management of painful diabetic neuropathy

Mitra Tavakoli, Rayaz Malik

Research output: Contribution to journalReview article

20 Citations (Scopus)


The commonest cause of peripheral neuropathy is diabetes and pain occurs in ∼ 30% of diabetic patients with neuropathy. It is extremely distressing for the patient and poses significant difficulties in management, as no treatment to date provides total relief and the side effects of therapy limit dose titration. Understanding the pathogenesis of diabetic neuropathy may lead to the development of new treatments for preventing nerve damage. Furthermore, a better understanding of the mechanisms that modulate pain may lead to more effective relief of painful symptoms. This review provides an update on the assessment and treatment of painful diabetic neuropathy.

Original languageEnglish
Pages (from-to)2969-2978
Number of pages10
JournalExpert Opinion on Pharmacotherapy
Issue number17
Publication statusPublished - Dec 2008
Externally publishedYes



  • Diabetic neuropathy
  • Pathogenetic treatment
  • Symptomatic therapy

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology

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