Lower Extremity Motor Evoked Potentials in Multiple Sclerosis

Seth M. Jones, Leopold Streletz, Vicki E. Raab, Robert L. Knobler, Fred D. Lublin

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Transcranial magnetic stimulation was performed on 25 patients with definite multiple sclerosis. Motor evoked potentials were recorded from the anterior tibial muscle. Central motor conduction time was calculated using the equation (F + M-1)/2 by stimulation of the common peroneal nerve. Motor evoked potentials were capable of detecting subclinical pyramidal tract lesions in multiple sclerosis. In patients with multiple sclerosis, the incidence of abnormality of motor and somatosensory evoked potentials was similar. Central motor conduction time was correlated with overall and pyramidal tract subscores on the Kurtzke Disability Status Scale and the Scripps Neurological Rating Scale. Central motor conduction time abnormalities correlated best with the presence of a Babinski's sign but also correlated significantly with weakness and hyperreflexia.

Original languageEnglish
Pages (from-to)944-948
Number of pages5
JournalArchives of Neurology
Volume48
Issue number9
DOIs
Publication statusPublished - 1991
Externally publishedYes

Fingerprint

Motor Evoked Potentials
Multiple Sclerosis
Lower Extremity
Pyramidal Tracts
Babinski's Reflex
Abnormal Reflexes
Peroneal Nerve
Somatosensory Evoked Potentials
Transcranial Magnetic Stimulation
Skeletal Muscle
Incidence
Evoked Potentials

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Lower Extremity Motor Evoked Potentials in Multiple Sclerosis. / Jones, Seth M.; Streletz, Leopold; Raab, Vicki E.; Knobler, Robert L.; Lublin, Fred D.

In: Archives of Neurology, Vol. 48, No. 9, 1991, p. 944-948.

Research output: Contribution to journalArticle

Jones, Seth M. ; Streletz, Leopold ; Raab, Vicki E. ; Knobler, Robert L. ; Lublin, Fred D. / Lower Extremity Motor Evoked Potentials in Multiple Sclerosis. In: Archives of Neurology. 1991 ; Vol. 48, No. 9. pp. 944-948.
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