Localized MRI and histological image correlation in a canine model of duchenne muscular dystrophy

A. Eresen, S. McConnell, S. M. Birch, J. F. Griffin, J. N. Kornegay, Jim Ji

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Duchenne Muscular Dystrophy (DMD) is a fatal X-linked disorder. Therapeutic assessments currently require muscle biopsy to ascertain information about the status of disease progression. MRI shows potential to be used in place of muscle biopsy for therapeutic assessments. In this work, localized histological data and various MRI parameters were correlated in a canine model of DMD. The results indicate several MRI parameters may be useful as biomarkers of disease progression.

Original languageEnglish
Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4083-4086
Number of pages4
Volume2016-October
ISBN (Electronic)9781457702204
DOIs
Publication statusPublished - 13 Oct 2016
Externally publishedYes
Event38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States
Duration: 16 Aug 201620 Aug 2016

Other

Other38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
CountryUnited States
CityOrlando
Period16/8/1620/8/16

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Keywords

  • Image registration
  • Image segmentation
  • MRI biomarkers

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Eresen, A., McConnell, S., Birch, S. M., Griffin, J. F., Kornegay, J. N., & Ji, J. (2016). Localized MRI and histological image correlation in a canine model of duchenne muscular dystrophy. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 (Vol. 2016-October, pp. 4083-4086). [7591624] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2016.7591624