Liver infarction in a woman with systemic lupus erythematosus and secondary anti-phospholipid and HELLP syndrome

K. Sakhel, I. M. Usta, A. Hannoun, T. Arayssi, Anwar H. Nassar

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5 Citations (Scopus)


We report a 39-year-old primigravida, a case of systemic lupus erythematosus (SLE) and secondary anti-phospholipid syndrome (APS) with a smooth antenatal course who delivered by caesarean for non-reassuring foetal heart rate. On day 2 postoperatively, she developed a sudden severe colicky upper abdominal pain with tachypnoea, dyspnoea, and tachycardia, and blood pressure (BP) reaching 150/95 mmHg. Computed tomography of the abdomen revealed lesions consistent with liver infarction. She developed haemolytic anaemia, elevated liver enzymes, and low platelets (HELLP syndrome); heparin and methylprednisolone were started. On day 3, BP normalized, respiratory symptoms improved but abdominal symptoms persisted. Methylprednisolone was increased to 80 mg/day on day 8 when she had significant clinical response and was discharged on day 16. This case emphasizes that a morbid clinical course including liver infarction should be anticipated in patients with SLE and APS complicated with HELLP syndrome.

Original languageEnglish
Pages (from-to)405-408
Number of pages4
JournalScandinavian Journal of Rheumatology
Issue number5
Publication statusPublished - 1 Oct 2006


ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology

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