LANTHANIDES AND EXCITATION-CONTRACTION COUPLING IN GUINEA-PIG ILEAL LONGITUDINAL SMOOTH MUSCLE.

Christopher Triggle, D. J. Triggle

Research output: Contribution to journalArticle

Abstract

The response of guinea-pig ileal longitudinal smooth muscle to acetylcholine and related muscarinic stimulants are of considerable interest because both the phasic (initial, fast) and tonic (later, slow) components of the contractile response show a very steep dependence upon Ca**2** plus and are very sensitive to La**3** plus . Hence, a comparative survey of the lanthanide series with a range of ionic radii very similar to that of Ca**2** plus (Ca**2** plus equals 0. 99A, La**3** plus equals 1. 006A, Lu**3** plus equals 0. 85A), which adopt the same 8-coordination, are subject to the same steric effects as Ca**2** plus and whose chemistry is in general very similar to that of the group IIA cations, is of interest.

Original languageEnglish
Pages (from-to)682-686
Number of pages5
Journal[No source information available]
Publication statusPublished - 1800
Externally publishedYes

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Rare earth elements
Muscle
Positive ions

ASJC Scopus subject areas

  • Engineering(all)

Cite this

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title = "LANTHANIDES AND EXCITATION-CONTRACTION COUPLING IN GUINEA-PIG ILEAL LONGITUDINAL SMOOTH MUSCLE.",
abstract = "The response of guinea-pig ileal longitudinal smooth muscle to acetylcholine and related muscarinic stimulants are of considerable interest because both the phasic (initial, fast) and tonic (later, slow) components of the contractile response show a very steep dependence upon Ca**2** plus and are very sensitive to La**3** plus . Hence, a comparative survey of the lanthanide series with a range of ionic radii very similar to that of Ca**2** plus (Ca**2** plus equals 0. 99A, La**3** plus equals 1. 006A, Lu**3** plus equals 0. 85A), which adopt the same 8-coordination, are subject to the same steric effects as Ca**2** plus and whose chemistry is in general very similar to that of the group IIA cations, is of interest.",
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N2 - The response of guinea-pig ileal longitudinal smooth muscle to acetylcholine and related muscarinic stimulants are of considerable interest because both the phasic (initial, fast) and tonic (later, slow) components of the contractile response show a very steep dependence upon Ca**2** plus and are very sensitive to La**3** plus . Hence, a comparative survey of the lanthanide series with a range of ionic radii very similar to that of Ca**2** plus (Ca**2** plus equals 0. 99A, La**3** plus equals 1. 006A, Lu**3** plus equals 0. 85A), which adopt the same 8-coordination, are subject to the same steric effects as Ca**2** plus and whose chemistry is in general very similar to that of the group IIA cations, is of interest.

AB - The response of guinea-pig ileal longitudinal smooth muscle to acetylcholine and related muscarinic stimulants are of considerable interest because both the phasic (initial, fast) and tonic (later, slow) components of the contractile response show a very steep dependence upon Ca**2** plus and are very sensitive to La**3** plus . Hence, a comparative survey of the lanthanide series with a range of ionic radii very similar to that of Ca**2** plus (Ca**2** plus equals 0. 99A, La**3** plus equals 1. 006A, Lu**3** plus equals 0. 85A), which adopt the same 8-coordination, are subject to the same steric effects as Ca**2** plus and whose chemistry is in general very similar to that of the group IIA cations, is of interest.

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