Interspecific variation of olfactory preferences in flies, mice, and humans

Diogo Manoel, Melanie Makhlouf, Antonio Scialdone, Luis Miguel Rodrigues Saraiva

Research output: Contribution to journalArticle

Abstract

Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a previous study by Mandairon et al., which suggested that the olfactory preferences of mice and humans are similar. A probabilistic examination revealed that underpowered studies can result in spurious significant correlations, which can account for the differences between both studies. Future analyses aimed at dissecting the olfactory preferences across species need to test large numbers of odorants to stress-test the model proposed here and identify robust associations.

Original languageEnglish
Pages (from-to)7-9
Number of pages3
JournalChemical Senses
Volume44
Issue number1
DOIs
Publication statusPublished - 1 Jan 2019

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Diptera
Exercise Test
Odorants

ASJC Scopus subject areas

  • Physiology
  • Sensory Systems
  • Physiology (medical)
  • Behavioral Neuroscience

Cite this

Interspecific variation of olfactory preferences in flies, mice, and humans. / Manoel, Diogo; Makhlouf, Melanie; Scialdone, Antonio; Rodrigues Saraiva, Luis Miguel.

In: Chemical Senses, Vol. 44, No. 1, 01.01.2019, p. 7-9.

Research output: Contribution to journalArticle

Manoel, Diogo ; Makhlouf, Melanie ; Scialdone, Antonio ; Rodrigues Saraiva, Luis Miguel. / Interspecific variation of olfactory preferences in flies, mice, and humans. In: Chemical Senses. 2019 ; Vol. 44, No. 1. pp. 7-9.
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