Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery

Stephen Atkin, Anne Marie Coady, Michael C. White, Bruce Mathew

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

A female aged 53 years was found to have a suprasellar lesion, which was shown to be a Rathke's cyst after removal by transsphenoidal surgery. She presented 16 days postoperatively, and following two grand mal seizures was found to be profoundly hyponatraemic (sodium 101 mmol/l). She was initially thought to have the syndrome of inappropriate antidiuretic hormone and was treated accordingly, but central venous pressure measurement revealed the hypovolaemia of cerebral salt wasting syndrome. The patient subsequently developed severe neurological sequelae after the correction of her hyponatraemia, following the development of extrapontine myelinolysis. Cerebral salt wasting syndrome is a rare cause of hyponatraemia following pituitary transsphenoidal surgery, which may mimic the syndrome of inappropriate antidiuretic hormone secretion. This case emphasizes the poor prognosis that may result from the rapid correction of profound hyponatraemia.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalEuropean Journal of Endocrinology
Volume135
Issue number2
Publication statusPublished - Aug 1996
Externally publishedYes

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Wasting Syndrome
Hyponatremia
Salts
Central Pontine Myelinolysis
Inappropriate ADH Syndrome
Hypovolemia
Central Venous Pressure
Vasopressins
Cysts
Seizures
Sodium

ASJC Scopus subject areas

  • Endocrinology

Cite this

Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery. / Atkin, Stephen; Coady, Anne Marie; White, Michael C.; Mathew, Bruce.

In: European Journal of Endocrinology, Vol. 135, No. 2, 08.1996, p. 245-247.

Research output: Contribution to journalArticle

Atkin, Stephen ; Coady, Anne Marie ; White, Michael C. ; Mathew, Bruce. / Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery. In: European Journal of Endocrinology. 1996 ; Vol. 135, No. 2. pp. 245-247.
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