Human Microbiome and its Association With Health and Diseases

Asmaa A. Althani, Hany E. Marei, Wedad S. Hamdi, Gheyath K. Nasrallah, Mohamed E. El Zowalaty, Souhaila M. Al Khodor, Maha Al-Asmakh, Hassan Abdel-Aziz, Carlo Cenciarelli

Research output: Contribution to journalReview article

45 Citations (Scopus)

Abstract

Human microbiota are distinct communities of microorganisms that resides at different body niches. Exploration of the human microbiome has become a reality due to the availability of powerful metagenomics and metatranscriptomic analysis technologies. Recent advances in sequencing and bioinformatics over the past decade help provide a deep insight into the nature of the host-microbial interactions and identification of potential deriver genes and pathways associated with human health, well-being, and predisposition to different diseases. In the present review, we outline recent studies devoted to elucidate the possible link between the microbiota and various type of diseases. The present review also highlights the potential utilization of microbiota as a potential therapeutic option to treat a wide array of human diseases.

Original languageEnglish
Pages (from-to)1688-1694
Number of pages7
JournalJournal of Cellular Physiology
Volume231
Issue number8
DOIs
Publication statusPublished - 1 Aug 2016

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ASJC Scopus subject areas

  • Medicine(all)
  • Physiology
  • Clinical Biochemistry
  • Cell Biology

Cite this

Althani, A. A., Marei, H. E., Hamdi, W. S., Nasrallah, G. K., El Zowalaty, M. E., Al Khodor, S. M., Al-Asmakh, M., Abdel-Aziz, H., & Cenciarelli, C. (2016). Human Microbiome and its Association With Health and Diseases. Journal of Cellular Physiology, 231(8), 1688-1694. https://doi.org/10.1002/jcp.25284