Human and mouse disorders of pigmentation

Richard A. Spritz, Pei Wen Chiang, Naoki Oiso, Asem Alkhateeb

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Disorders of pigmentation were among the first genetic diseases ever recognized because of their visually striking clinical phenotypes, resulting from defects of pigmentary melanocytes. Recent years have seen remarkable progress in understanding these diseases, largely as a result of the systematic parallel study of human patients and inbred mice with similar phenotypes. Our understanding of disorders of pigmentation indicates that these diseases may be most usefully considered as abnormalities of melanocyte development, function, or survival.

Original languageEnglish
Pages (from-to)284-289
Number of pages6
JournalCurrent Opinion in Genetics and Development
Volume13
Issue number3
DOIs
Publication statusPublished - Jun 2003
Externally publishedYes

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Pigmentation Disorders
Melanocytes
Phenotype
Inborn Genetic Diseases
Survival

ASJC Scopus subject areas

  • Genetics

Cite this

Human and mouse disorders of pigmentation. / Spritz, Richard A.; Chiang, Pei Wen; Oiso, Naoki; Alkhateeb, Asem.

In: Current Opinion in Genetics and Development, Vol. 13, No. 3, 06.2003, p. 284-289.

Research output: Contribution to journalArticle

Spritz, RA, Chiang, PW, Oiso, N & Alkhateeb, A 2003, 'Human and mouse disorders of pigmentation', Current Opinion in Genetics and Development, vol. 13, no. 3, pp. 284-289. https://doi.org/10.1016/S0959-437X(03)00059-5
Spritz, Richard A. ; Chiang, Pei Wen ; Oiso, Naoki ; Alkhateeb, Asem. / Human and mouse disorders of pigmentation. In: Current Opinion in Genetics and Development. 2003 ; Vol. 13, No. 3. pp. 284-289.
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