Higher-order structure of chromatin and chromosomes

Christopher L. Woodcock, Stefan Dimitrov

Research output: Contribution to journalReview article

211 Citations (Scopus)


The linear array of nucleosomes that comprises the primary structure of chromatin is folded and condensed to varying degrees in nuclei and chromosomes forming 'higher order structures'. We discuss the recent findings from novel experimental approaches that have yielded significant new information on the different hierarchical levels of chromatin folding and their functional significance.

Original languageEnglish
Pages (from-to)130-135
Number of pages6
JournalCurrent Opinion in Genetics and Development
Issue number2
Publication statusPublished - 1 Apr 2001


ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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