Les predispositions hereditaires aux cancers du sein: Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien

Translated title of the contribution: Hereditary pedisposition to breast cancer: Epidemiologic and clinico-anatomic features about 11 families in the central region of Tunisia

Slim Ben Ahméd, Kamel Monastiri, Lotfi Chouchane, Mohamed El Ouali, Sadok Korbi, Chakib Kraiem, Hédi Khairi, Yves Jean Bignon

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Five to 10 % of women with breast cancer have a positive family history of breast cancer (9,1 % in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.

Original languageFrench
Pages (from-to)111-116
Number of pages6
JournalTunisie Medicale
Volume75
Issue number3
Publication statusPublished - Mar 1997
Externally publishedYes

Fingerprint

Tunisia
Breast Neoplasms
Pregnancy Rate
Age of Onset
Neoplasms
Economics

Keywords

  • Breast cancer
  • Hereditary predisposition
  • Screening

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ahméd, S. B., Monastiri, K., Chouchane, L., El Ouali, M., Korbi, S., Kraiem, C., ... Bignon, Y. J. (1997). Les predispositions hereditaires aux cancers du sein: Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien. Tunisie Medicale, 75(3), 111-116.

Les predispositions hereditaires aux cancers du sein : Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien. / Ahméd, Slim Ben; Monastiri, Kamel; Chouchane, Lotfi; El Ouali, Mohamed; Korbi, Sadok; Kraiem, Chakib; Khairi, Hédi; Bignon, Yves Jean.

In: Tunisie Medicale, Vol. 75, No. 3, 03.1997, p. 111-116.

Research output: Contribution to journalArticle

Ahméd, SB, Monastiri, K, Chouchane, L, El Ouali, M, Korbi, S, Kraiem, C, Khairi, H & Bignon, YJ 1997, 'Les predispositions hereditaires aux cancers du sein: Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien', Tunisie Medicale, vol. 75, no. 3, pp. 111-116.
Ahméd, Slim Ben ; Monastiri, Kamel ; Chouchane, Lotfi ; El Ouali, Mohamed ; Korbi, Sadok ; Kraiem, Chakib ; Khairi, Hédi ; Bignon, Yves Jean. / Les predispositions hereditaires aux cancers du sein : Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien. In: Tunisie Medicale. 1997 ; Vol. 75, No. 3. pp. 111-116.
@article{cf8d33965f7e40f9a1675df092beb24b,
title = "Les predispositions hereditaires aux cancers du sein: Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien",
abstract = "Five to 10 {\%} of women with breast cancer have a positive family history of breast cancer (9,1 {\%} in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.",
keywords = "Breast cancer, Hereditary predisposition, Screening",
author = "Ahm{\'e}d, {Slim Ben} and Kamel Monastiri and Lotfi Chouchane and {El Ouali}, Mohamed and Sadok Korbi and Chakib Kraiem and H{\'e}di Khairi and Bignon, {Yves Jean}",
year = "1997",
month = "3",
language = "French",
volume = "75",
pages = "111--116",
journal = "Tunisie Medicale",
issn = "0041-4131",
publisher = "Maison du Medicine",
number = "3",

}

TY - JOUR

T1 - Les predispositions hereditaires aux cancers du sein

T2 - Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien

AU - Ahméd, Slim Ben

AU - Monastiri, Kamel

AU - Chouchane, Lotfi

AU - El Ouali, Mohamed

AU - Korbi, Sadok

AU - Kraiem, Chakib

AU - Khairi, Hédi

AU - Bignon, Yves Jean

PY - 1997/3

Y1 - 1997/3

N2 - Five to 10 % of women with breast cancer have a positive family history of breast cancer (9,1 % in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.

AB - Five to 10 % of women with breast cancer have a positive family history of breast cancer (9,1 % in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.

KW - Breast cancer

KW - Hereditary predisposition

KW - Screening

UR - http://www.scopus.com/inward/record.url?scp=0031083523&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031083523&partnerID=8YFLogxK

M3 - Article

C2 - 9506032

AN - SCOPUS:0031083523

VL - 75

SP - 111

EP - 116

JO - Tunisie Medicale

JF - Tunisie Medicale

SN - 0041-4131

IS - 3

ER -