Abstract
Five to 10 % of women with breast cancer have a positive family history of breast cancer (9,1 % in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.
| Original language | French |
|---|---|
| Pages (from-to) | 111-116 |
| Number of pages | 6 |
| Journal | Tunisie Medicale |
| Volume | 75 |
| Issue number | 3 |
| Publication status | Published - Mar 1997 |
| Externally published | Yes |
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Keywords
- Breast cancer
- Hereditary predisposition
- Screening
ASJC Scopus subject areas
- Medicine(all)
Cite this
Les predispositions hereditaires aux cancers du sein : Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien. / Ahméd, Slim Ben; Monastiri, Kamel; Chouchane, Lotfi; El Ouali, Mohamed; Korbi, Sadok; Kraiem, Chakib; Khairi, Hédi; Bignon, Yves Jean.
In: Tunisie Medicale, Vol. 75, No. 3, 03.1997, p. 111-116.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Les predispositions hereditaires aux cancers du sein
T2 - Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien
AU - Ahméd, Slim Ben
AU - Monastiri, Kamel
AU - Chouchane, Lotfi
AU - El Ouali, Mohamed
AU - Korbi, Sadok
AU - Kraiem, Chakib
AU - Khairi, Hédi
AU - Bignon, Yves Jean
PY - 1997/3
Y1 - 1997/3
N2 - Five to 10 % of women with breast cancer have a positive family history of breast cancer (9,1 % in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.
AB - Five to 10 % of women with breast cancer have a positive family history of breast cancer (9,1 % in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.
KW - Breast cancer
KW - Hereditary predisposition
KW - Screening
UR - http://www.scopus.com/inward/record.url?scp=0031083523&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031083523&partnerID=8YFLogxK
M3 - Article
VL - 75
SP - 111
EP - 116
JO - Tunisie Medicale
JF - Tunisie Medicale
SN - 0041-4131
IS - 3
ER -