Les predispositions hereditaires aux cancers du sein: Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien

Translated title of the contribution: Hereditary pedisposition to breast cancer: Epidemiologic and clinico-anatomic features about 11 families in the central region of Tunisia

Slim Ben Ahméd, Kamel Monastiri, Lotfi Chouchane, Mohamed El Ouali, Sadok Korbi, Chakib Kraiem, Hédi Khairi, Yves Jean Bignon

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Five to 10 % of women with breast cancer have a positive family history of breast cancer (9,1 % in our study). We designed a comparative study to investigate the potential differences of epidemiologic, clinicopathologic profiles between patients with sporadic breast cancer and those with hereditary breast cancer. Eleven case families (of 27 patients living in the central region of Tunisia accrued during the periode between 1990 to 1995) are included in the study. Compared to sporadic breast cancer patients, those with hereditary breast cancer are characterized by younger ages of the cancer onset (p = 0,04), higher social and economic situations (p -0,005), lower pregnancy rate and lower tumor size (p = 0,005). A good knowledge of genetic factors involved in breast cancer may have important consequences in screening high risk individuals from affected families.

Original languageFrench
Pages (from-to)111-116
Number of pages6
JournalTunisie Medicale
Volume75
Issue number3
Publication statusPublished - 1 Mar 1997

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Keywords

  • Breast cancer
  • Hereditary predisposition
  • Screening

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ahméd, S. B., Monastiri, K., Chouchane, L., El Ouali, M., Korbi, S., Kraiem, C., Khairi, H., & Bignon, Y. J. (1997). Les predispositions hereditaires aux cancers du sein: Profils epidemiologique et anatomoclinique de 11 familles dans le centre tunisien. Tunisie Medicale, 75(3), 111-116.