Henoch-Schonlein purpura and streptococcal infection: A prospective case-control study

Mahmoud Al-Sheyyab, Anwar Batieha, Hatem El-Shanti, Azhar Daoud

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28 Citations (Scopus)


A prospective, matched, case-control study conducted over a period of 3 years was designed to examine the association of group A β-haemolytic streptococcal infections and Henoch-Schonlein purpura. Demographic and clinical data were collected as well as measurement of antistreptolysin O titres and throat swab culture on all children admitted with Henoch-Schonlein purpura, as well as their marched controls. Antistreptolysin O titre positivity was associated with a 10-fold increase in the risk of Henoch-Schonlein purpura. Renal involvement was common among cases with positive antistreptolysin O titres (27%) compared with cases with a negative titre (8%) but this difference has no statistical significance.

Original languageEnglish
Pages (from-to)253-255
Number of pages3
JournalAnnals of Tropical Paediatrics
Issue number3
Publication statusPublished - Sep 1999
Externally publishedYes


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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