Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese

Ted D. Adams, Robert C. Pendleton, Michael B. Strong, Ronette L. Kolotkin, James M. Walker, Sheldon E. Litwin, Wael K. Berjaoui, Michael J. Lamonte, Tom V. Cloward, Erick Avelar, Theophilus E. Owan, Robert T. Nuttall, Richard E. Gress, Ross D. Crosby, Paul N. Hopkins, Eliot A. Brinton, Wayne D. Rosamond, Gail A. Wiebke, Frank G. Yanowitz, Robert J. Farney & 4 others R. Chad Halverson, Steven C. Simper, Sherman C. Smith, Steven Hunt

Research output: Contribution to journalArticle

91 Citations (Scopus)

Abstract

Favorable health outcomes at 2 years postbariatric surgery have been reported. With exception of the Swedish Obesity Subjects (SOS) study, these studies have been surgical case series, comparison of surgery types, or surgery patients compared to subjects enrolled in planned nonsurgical intervention. This study measured gastric bypass effectiveness when compared to two separate severely obese groups not participating in designed weight-loss intervention. Three groups of severely obese subjects (N = 1,156, BMI 35 kg/m 2) were studied: gastric bypass subjects (n = 420), subjects seeking gastric bypass but did not have surgery (n = 415), and population-based subjects not seeking surgery (n = 321). Participants were studied at baseline and 2 years. Quantitative outcome measures as well as prevalence, incidence, and resolution rates of categorical health outcome variables were determined. All quantitative variables (BMI, blood pressure, lipids, diabetes-related variables, resting metabolic rate (RMR), sleep apnea, and health-related quality of life) improved significantly in the gastric bypass group compared with each comparative group (all P 0.0001, except for diastolic blood pressure and the short form (SF-36) health survey mental component score at P 0.01). Diabetes, dyslipidemia, and hypertension resolved much more frequently in the gastric bypass group than in the comparative groups (all P 0.001). In the surgical group, beneficial changes of almost all quantitative variables correlated significantly with the decrease in BMI. We conclude that Roux-en-Y gastric bypass surgery when compared to severely obese groups not enrolled in planned weight-loss intervention was highly effective for weight loss, improved health-related quality of life, and resolution of major obesity-associated complications measured at 2 years.

Original languageEnglish
Pages (from-to)121-130
Number of pages10
JournalObesity
Volume18
Issue number1
DOIs
Publication statusPublished - Jan 2010
Externally publishedYes

Fingerprint

Gastric Bypass
Health
Weight Loss
Blood Pressure
Obesity
Quality of Life
Basal Metabolism
Sleep Apnea Syndromes
Dyslipidemias
Health Surveys
Outcome Assessment (Health Care)
Hypertension
Lipids
Incidence
Population

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

Cite this

Adams, T. D., Pendleton, R. C., Strong, M. B., Kolotkin, R. L., Walker, J. M., E. Litwin, S., ... Hunt, S. (2010). Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. Obesity, 18(1), 121-130. https://doi.org/10.1038/oby.2009.178

Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. / Adams, Ted D.; Pendleton, Robert C.; Strong, Michael B.; Kolotkin, Ronette L.; Walker, James M.; E. Litwin, Sheldon; Berjaoui, Wael K.; Lamonte, Michael J.; Cloward, Tom V.; Avelar, Erick; Owan, Theophilus E.; Nuttall, Robert T.; Gress, Richard E.; Crosby, Ross D.; Hopkins, Paul N.; Brinton, Eliot A.; Rosamond, Wayne D.; Wiebke, Gail A.; Yanowitz, Frank G.; Farney, Robert J.; Halverson, R. Chad; Simper, Steven C.; Smith, Sherman C.; Hunt, Steven.

In: Obesity, Vol. 18, No. 1, 01.2010, p. 121-130.

Research output: Contribution to journalArticle

Adams, TD, Pendleton, RC, Strong, MB, Kolotkin, RL, Walker, JM, E. Litwin, S, Berjaoui, WK, Lamonte, MJ, Cloward, TV, Avelar, E, Owan, TE, Nuttall, RT, Gress, RE, Crosby, RD, Hopkins, PN, Brinton, EA, Rosamond, WD, Wiebke, GA, Yanowitz, FG, Farney, RJ, Halverson, RC, Simper, SC, Smith, SC & Hunt, S 2010, 'Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese', Obesity, vol. 18, no. 1, pp. 121-130. https://doi.org/10.1038/oby.2009.178
Adams TD, Pendleton RC, Strong MB, Kolotkin RL, Walker JM, E. Litwin S et al. Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. Obesity. 2010 Jan;18(1):121-130. https://doi.org/10.1038/oby.2009.178
Adams, Ted D. ; Pendleton, Robert C. ; Strong, Michael B. ; Kolotkin, Ronette L. ; Walker, James M. ; E. Litwin, Sheldon ; Berjaoui, Wael K. ; Lamonte, Michael J. ; Cloward, Tom V. ; Avelar, Erick ; Owan, Theophilus E. ; Nuttall, Robert T. ; Gress, Richard E. ; Crosby, Ross D. ; Hopkins, Paul N. ; Brinton, Eliot A. ; Rosamond, Wayne D. ; Wiebke, Gail A. ; Yanowitz, Frank G. ; Farney, Robert J. ; Halverson, R. Chad ; Simper, Steven C. ; Smith, Sherman C. ; Hunt, Steven. / Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. In: Obesity. 2010 ; Vol. 18, No. 1. pp. 121-130.
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