Genetic testing and genomic analysis: A debate on ethical, social and legal issues in the Arab world with a focus on Qatar

Hatem Shanti, Lotfi Chouchane, Ramin Badii, Imed Gallouzi, Paolo Gasparini

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

In 2013 both Saudi Arabia and Qatar launched genome projects with the aim of providing information for better diagnosis, treatment and prevention of diseases and, ultimately to realize personalized medicine by sequencing hundred thousands samples. These population based genome activities raise a series of relevant ethical, legal and social issues general, related to the specific population structure as well as to the Islamic perspective on genomic analysis and genetic testing. To contribute to the debate, the Authors after reviewing the existing literature and taking advantage of their professional experience in the field and in the geographic area, discuss and provide their opinions. In particular, the Authors focus on the impact of consanguinity on population structure and disease frequency in the Arab world, on genetic testing and genomic analysis (i.e. technical aspects, impact, etc.) and on their regulations. A comparison between the Islamic perspective and the ethical, social and legal issues raised in other population contexts is also carried. In conclusion, this opinion article with an up-to-date contribution to the discussion on the relevance and impact of genomic analysis and genetic testing in the Arab world, might help in producing specific national guidelines on genetic testing and genomic analysis and help accelerate the implementation and roll out of genome projects in Muslim countries and more specifically in Qatar, and other countries of the Gulf.

Original languageEnglish
Article number358
JournalJournal of Translational Medicine
Volume13
Issue number1
DOIs
Publication statusPublished - 14 Nov 2015

Fingerprint

Arab World
Qatar
Genetic Testing
Genes
Testing
Genome
Population
Consanguinity
Islam
Precision Medicine
Saudi Arabia
Medicine
Guidelines

Keywords

  • Consanguinity
  • Genetic testing
  • Genome projects
  • Genomic analysis
  • Islamic view

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Genetic testing and genomic analysis : A debate on ethical, social and legal issues in the Arab world with a focus on Qatar. / Shanti, Hatem; Chouchane, Lotfi; Badii, Ramin; Gallouzi, Imed; Gasparini, Paolo.

In: Journal of Translational Medicine, Vol. 13, No. 1, 358, 14.11.2015.

Research output: Contribution to journalReview article

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